Oxytocin attenuates respiratory depression and reduces mortality from fentanyl and the combination of xylazine-fentanyl in rats.

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Title: Oxytocin attenuates respiratory depression and reduces mortality from fentanyl and the combination of xylazine-fentanyl in rats.
Authors: Escobar JB; Department of Pharmacology and Physiology, The George Washington University, Washington, DC 20037, United States., Wainwright J; Department of Pharmacology and Physiology, The George Washington University, Washington, DC 20037, United States., Wang X; Department of Pharmacology and Physiology, The George Washington University, Washington, DC 20037, United States., Dergacheva O; Department of Pharmacology and Physiology, The George Washington University, Washington, DC 20037, United States., Kay MW; Department of Biomedical Engineering, The George Washington University, Washington, DC 20052, United States., Bethea JR; Department of Anatomy and Cell Biology, George Washington University, Washington, DC 20037, United States., Jain V; Department of Pulmonary, Critical Care, and Sleep Disorders Medicine, George Washington University, Washington, DC 20037, United States., Polotsky VY; Department of Anesthesiology and Critical Care Medicine, George Washington University, Washington, DC 20037, United States., Mendelowitz D; Department of Pharmacology and Physiology, The George Washington University, Washington, DC 20037, United States. Electronic address: dmendel@gwu.edu.
Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2026 Jul; Vol. 200, pp. 119535. Date of Electronic Publication: 2026 May 28.
Publication Type: Journal Article
Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1950-6007
DOI:10.1016/j.biopha.2026.119535