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Oxytocin attenuates respiratory depression and reduces mortality from fentanyl and the combination of xylazine-fentanyl in rats.

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Title: Oxytocin attenuates respiratory depression and reduces mortality from fentanyl and the combination of xylazine-fentanyl in rats.
Authors: Escobar JB; Department of Pharmacology and Physiology, The George Washington University, Washington, DC 20037, United States., Wainwright J; Department of Pharmacology and Physiology, The George Washington University, Washington, DC 20037, United States., Wang X; Department of Pharmacology and Physiology, The George Washington University, Washington, DC 20037, United States., Dergacheva O; Department of Pharmacology and Physiology, The George Washington University, Washington, DC 20037, United States., Kay MW; Department of Biomedical Engineering, The George Washington University, Washington, DC 20052, United States., Bethea JR; Department of Anatomy and Cell Biology, George Washington University, Washington, DC 20037, United States., Jain V; Department of Pulmonary, Critical Care, and Sleep Disorders Medicine, George Washington University, Washington, DC 20037, United States., Polotsky VY; Department of Anesthesiology and Critical Care Medicine, George Washington University, Washington, DC 20037, United States., Mendelowitz D; Department of Pharmacology and Physiology, The George Washington University, Washington, DC 20037, United States. Electronic address: dmendel@gwu.edu.
Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2026 Jul; Vol. 200, pp. 119535. Date of Electronic Publication: 2026 May 28.
Publication Type: Journal Article
Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Oxytocin attenuates respiratory depression and reduces mortality from fentanyl and the combination of xylazine-fentanyl in rats.
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  Data: <searchLink fieldCode="AU" term="%22Escobar+JB%22">Escobar JB</searchLink>; Department of Pharmacology and Physiology, The George Washington University, Washington, DC 20037, United States.<br /><searchLink fieldCode="AU" term="%22Wainwright+J%22">Wainwright J</searchLink>; Department of Pharmacology and Physiology, The George Washington University, Washington, DC 20037, United States.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Department of Pharmacology and Physiology, The George Washington University, Washington, DC 20037, United States.<br /><searchLink fieldCode="AU" term="%22Dergacheva+O%22">Dergacheva O</searchLink>; Department of Pharmacology and Physiology, The George Washington University, Washington, DC 20037, United States.<br /><searchLink fieldCode="AU" term="%22Kay+MW%22">Kay MW</searchLink>; Department of Biomedical Engineering, The George Washington University, Washington, DC 20052, United States.<br /><searchLink fieldCode="AU" term="%22Bethea+JR%22">Bethea JR</searchLink>; Department of Anatomy and Cell Biology, George Washington University, Washington, DC 20037, United States.<br /><searchLink fieldCode="AU" term="%22Jain+V%22">Jain V</searchLink>; Department of Pulmonary, Critical Care, and Sleep Disorders Medicine, George Washington University, Washington, DC 20037, United States.<br /><searchLink fieldCode="AU" term="%22Polotsky+VY%22">Polotsky VY</searchLink>; Department of Anesthesiology and Critical Care Medicine, George Washington University, Washington, DC 20037, United States.<br /><searchLink fieldCode="AU" term="%22Mendelowitz+D%22">Mendelowitz D</searchLink>; Department of Pharmacology and Physiology, The George Washington University, Washington, DC 20037, United States. Electronic address: dmendel@gwu.edu.
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  Data: <searchLink fieldCode="JN" term="%228213295%22">Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie</searchLink> [Biomed Pharmacother] 2026 Jul; Vol. 200, pp. 119535. <i>Date of Electronic Publication: </i>2026 May 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Editions+Scientifiques+Elsevier%22">Editions Scientifiques Elsevier </searchLink><i>Country of Publication: </i>France <i>NLM ID: </i>8213295 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1950-6007 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2207533322%22">07533322 </searchLink><i>NLM ISO Abbreviation: </i>Biomed Pharmacother <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.biopha.2026.119535
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        Text: English
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        StartPage: 119535
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      – TitleFull: Oxytocin attenuates respiratory depression and reduces mortality from fentanyl and the combination of xylazine-fentanyl in rats.
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              M: 07
              Text: 2026 Jul
              Type: published
              Y: 2026
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