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Genetically prioritized druggable targets for amyloid-β pathology highlight ACE as a therapeutic candidate in Alzheimer's disease.

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Title: Genetically prioritized druggable targets for amyloid-β pathology highlight ACE as a therapeutic candidate in Alzheimer's disease.
Authors: Kim JP; Department of Neurology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea., Lee H; Alzheimer's Disease Convergence Research Center, Samsung Medical Center, Seoul, Republic of Korea.; Department of Health Sciences and Technology, Sungkyunkwan University, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Seoul, Republic of Korea., Kim BH; Alzheimer's Disease Convergence Research Center, Samsung Medical Center, Seoul, Republic of Korea., Kang H; Department of Neurology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea., Shin D; Department of Neurology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea., Yim S; Department of Neurology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea., Kim S; Department of Neurology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea., Seo SW; Department of Neurology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea.; Alzheimer's Disease Convergence Research Center, Samsung Medical Center, Seoul, Republic of Korea., Kim HN; Department of Clinical Research Design & Evaluation, Sungkyunkwan University, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Seoul, Republic of Korea.; Center for Clinical Epidemiology, Sungkyunkwan University, Samsung Medical Center, Seoul, Republic of Korea.
Source: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2026 May 29, pp. 13872877261454540. Date of Electronic Publication: 2026 May 29.
Publication Type: Journal Article
Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 9814863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8908 (Electronic) Linking ISSN: 13872877 NLM ISO Abbreviation: J Alzheimers Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1875-8908
DOI:10.1177/13872877261454540