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Genetically prioritized druggable targets for amyloid-β pathology highlight ACE as a therapeutic candidate in Alzheimer's disease.

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Title: Genetically prioritized druggable targets for amyloid-β pathology highlight ACE as a therapeutic candidate in Alzheimer's disease.
Authors: Kim JP; Department of Neurology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea., Lee H; Alzheimer's Disease Convergence Research Center, Samsung Medical Center, Seoul, Republic of Korea.; Department of Health Sciences and Technology, Sungkyunkwan University, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Seoul, Republic of Korea., Kim BH; Alzheimer's Disease Convergence Research Center, Samsung Medical Center, Seoul, Republic of Korea., Kang H; Department of Neurology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea., Shin D; Department of Neurology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea., Yim S; Department of Neurology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea., Kim S; Department of Neurology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea., Seo SW; Department of Neurology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea.; Alzheimer's Disease Convergence Research Center, Samsung Medical Center, Seoul, Republic of Korea., Kim HN; Department of Clinical Research Design & Evaluation, Sungkyunkwan University, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Seoul, Republic of Korea.; Center for Clinical Epidemiology, Sungkyunkwan University, Samsung Medical Center, Seoul, Republic of Korea.
Source: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2026 May 29, pp. 13872877261454540. Date of Electronic Publication: 2026 May 29.
Publication Type: Journal Article
Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 9814863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8908 (Electronic) Linking ISSN: 13872877 NLM ISO Abbreviation: J Alzheimers Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Genetically prioritized druggable targets for amyloid-β pathology highlight ACE as a therapeutic candidate in Alzheimer's disease.
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  Data: <searchLink fieldCode="AU" term="%22Kim+JP%22">Kim JP</searchLink>; Department of Neurology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+H%22">Lee H</searchLink>; Alzheimer's Disease Convergence Research Center, Samsung Medical Center, Seoul, Republic of Korea.; Department of Health Sciences and Technology, Sungkyunkwan University, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+BH%22">Kim BH</searchLink>; Alzheimer's Disease Convergence Research Center, Samsung Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kang+H%22">Kang H</searchLink>; Department of Neurology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Shin+D%22">Shin D</searchLink>; Department of Neurology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yim+S%22">Yim S</searchLink>; Department of Neurology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Department of Neurology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Seo+SW%22">Seo SW</searchLink>; Department of Neurology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea.; Alzheimer's Disease Convergence Research Center, Samsung Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+HN%22">Kim HN</searchLink>; Department of Clinical Research Design & Evaluation, Sungkyunkwan University, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Seoul, Republic of Korea.; Center for Clinical Epidemiology, Sungkyunkwan University, Samsung Medical Center, Seoul, Republic of Korea.
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  Data: <searchLink fieldCode="JN" term="%229814863%22">Journal of Alzheimer's disease : JAD</searchLink> [J Alzheimers Dis] 2026 May 29, pp. 13872877261454540. <i>Date of Electronic Publication: </i>2026 May 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22SAGE+Publications%22">SAGE Publications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9814863 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1875-8908 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213872877%22">13872877 </searchLink><i>NLM ISO Abbreviation: </i>J Alzheimers Dis <i>Subsets: </i>MEDLINE
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        Value: 10.1177/13872877261454540
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        Text: English
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              Text: 2026 May 29
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