Fluorinated Ultralong-Acting Neuromuscular Blocking Agent with Improved Activity Profile and Biosafety for the Development of Blockade and Reversal Partner Drugs.

Saved in:
Bibliographic Details
Title: Fluorinated Ultralong-Acting Neuromuscular Blocking Agent with Improved Activity Profile and Biosafety for the Development of Blockade and Reversal Partner Drugs.
Authors: Gan SX; Department of Chemistry, Fudan University, 2205 Songhu Road, Shanghai 200438, China., Zhang RL; Department of Chemistry, Fudan University, 2205 Songhu Road, Shanghai 200438, China., Guo C; Department of Chemistry, Fudan University, 2205 Songhu Road, Shanghai 200438, China., Qi QY; State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, University of Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China., Feng K; State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, University of Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China., Yu SB; State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, University of Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China., Wang H; Department of Chemistry, Fudan University, 2205 Songhu Road, Shanghai 200438, China., Zhou W; Department of Chemistry, Fudan University, 2205 Songhu Road, Shanghai 200438, China., Zhao G; School of Materials Science and Engineering, Harbin Institute of Technology, Shenzhen 518055, China.; Shinewin Pharmaceuticals, 108 Yuxin Road, Suzhou, Jiangsu 215123, China., Zhang DW; Department of Chemistry, Fudan University, 2205 Songhu Road, Shanghai 200438, China., Li ZT; Department of Chemistry, Fudan University, 2205 Songhu Road, Shanghai 200438, China.; State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, University of Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China.
Source: Journal of medicinal chemistry [J Med Chem] 2026 Jun 11; Vol. 69 (11), pp. 13966-13979. Date of Electronic Publication: 2026 May 29.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1520-4804
DOI:10.1021/acs.jmedchem.6c01353