Cross-clade vaccination to overcome sarbecovirus or merbecovirus neutralization gaps.

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Title: Cross-clade vaccination to overcome sarbecovirus or merbecovirus neutralization gaps.
Authors: Chia WN; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore; Leyden Labs Asia, Singapore, Singapore., Zhu F; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore., Cheng SMS; Public Health Laboratory Sciences, School of Public Health, LKS Faculty of Medicine, Hong Kong University, Pokfulam, Hong Kong., Yap WC; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore; Infectious Diseases Translational Research Programme, Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore., Alshukairi AN; King Faisal Specialist Hospital and Research Center, Jeddah, Kingdom of Saudi Arabia; College of Medicine, Alfaisal University, Riyadh, Kingdom of Saudi Arabia., Mah YY; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore; Infectious Diseases Translational Research Programme, Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore., Mayxay M; Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Microbiology Laboratory, Mahosot Hospital, Ministry of Health, Vientiane, Laos; Unit for Health Evidence and Policy (UHEP), Institute of Research and Education Development, University of Health Sciences, Ministry of Health, Vientiane, Lao People's Democratic Republic; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore., Chansamouth V; Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Microbiology Laboratory, Mahosot Hospital, Ministry of Health, Vientiane, Laos., Letizia A; Naval Medical Research Unit INDO PACIFIC, Singapore, Singapore., Lim BL; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore; Infectious Diseases Translational Research Programme, Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore., Wang Y; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore; Biomedical Synthetic Biology Research Center, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China., Kwek MSS; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore., Evans TS; Epicenter for Disease Dynamics, One Health Institute, School of Veterinary Medicine, University of California, Davis, Davis, CA, USA; Infectious Diseases and Vaccinology Division, School of Public Health & Department of Integrative Biology, University of California, Berkeley, Berkeley, CA, USA., Aung O; Epicenter for Disease Dynamics, One Health Institute, School of Veterinary Medicine, University of California, Davis, Davis, CA, USA., Thu HM; Department of Medical Research, Dagon Township, Yangon, Myanmar., Johnson CK; Epicenter for Disease Dynamics, One Health Institute, School of Veterinary Medicine, University of California, Davis, Davis, CA, USA., Wang Y; Guangzhou National Laboratory, Guangzhou, China., Zhao J; Guangzhou National Laboratory, Guangzhou, China., Manning JE; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Rockville, MD, USA; International Center of Excellence in Research Cambodia, National Institute of Allergy and Infectious Diseases, Phnom Penh, Cambodia., Yek C; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Rockville, MD, USA; International Center of Excellence in Research Cambodia, National Institute of Allergy and Infectious Diseases, Phnom Penh, Cambodia., Lon C; International Center of Excellence in Research Cambodia, National Institute of Allergy and Infectious Diseases, Phnom Penh, Cambodia., Heng S; Communicable Disease Control Department, Ministry of Health, Phnom Penh, Cambodia., Ly S; Communicable Disease Control Department, Ministry of Health, Phnom Penh, Cambodia., Leang R; National Center for Parasitology, Entomology and Malaria Control, Ministry of Health, Phnom Penh, Cambodia., Huy R; National Center for Parasitology, Entomology and Malaria Control, Ministry of Health, Phnom Penh, Cambodia., Dewantari AK; Exeins Health Initiative, South Jakarta, Indonesia., Yudhaputri FA; Exeins Health Initiative, South Jakarta, Indonesia., Myint KSA; Exeins Health Initiative, South Jakarta, Indonesia., Rubach MP; Kilimajaro Christian Medical Centre, Moshi, Tanzania; Duke Global Health Institute, Duke University, Durham, NC, USA., Crump JA; Kilimajaro Christian Medical Centre, Moshi, Tanzania; Duke Global Health Institute, Duke University, Durham, NC, USA; Centre for International Health, University of Otago, Dunedin, New Zealand; Division of Infectious Diseases and International Health, Department of Medicine, Duke University Medical Centre, Durham, NC, USA., Maro VP; Kilimajaro Christian Medical Centre, Moshi, Tanzania., Moreland NJ; Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand., Paterson A; Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand., Charlewood R; Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand; New Zealand Blood Service, Auckland, New Zealand., Song J; Infectious Diseases Translational Research Programme, Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore., Chen S; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore., Tan WY; Infectious Diseases Translational Research Programme, Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore., Mok CKP; S. H. Ho Research Centre for Infectious Diseases, Faculty of Medicine, Chinese University of Hong Kong, Shatin, Hong Kong., Hor CHH; Department of Chemistry, Faculty of Science, Hong Kong Baptist University, Kowloon, Hong Kong., Lye D; Communicable Disease Agency, National Centre for Infectious Diseases, Singapore, Singapore; National Centre for Infectious Diseases, Singapore, Singapore; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Lee Kong Chian School of Medicine, Nanyang Technology University, Singapore, Singapore; Tan Tock Seng Hospital, Singapore, Singapore., Hui DS; S. H. Ho Research Centre for Infectious Diseases, Faculty of Medicine, Chinese University of Hong Kong, Shatin, Hong Kong., Young BE; National Centre for Infectious Diseases, Singapore, Singapore; Lee Kong Chian School of Medicine, Nanyang Technology University, Singapore, Singapore; Tan Tock Seng Hospital, Singapore, Singapore., Peiris M; Public Health Laboratory Sciences, School of Public Health, LKS Faculty of Medicine, Hong Kong University, Pokfulam, Hong Kong., Wang LF; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore. Electronic address: linfa.wang@duke-nus.edu.sg., Tan CW; Infectious Diseases Translational Research Programme, Department of Microbiology and Immunology, National University of Singapore, Singapore, Singapore; Infectious Diseases Research & Training Office, National Centre for Infectious Diseases, Singapore, Singapore. Electronic address: gmstanc@nus.edu.sg.
Source: Cell reports [Cell Rep] 2026 Jun 23; Vol. 45 (6), pp. 117444. Date of Electronic Publication: 2026 May 28.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2211-1247
DOI:10.1016/j.celrep.2026.117444