Biologics and small molecules for perianal Crohn's disease: a systematic review and meta-analyses of randomized placebo-controlled trials.

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Title: Biologics and small molecules for perianal Crohn's disease: a systematic review and meta-analyses of randomized placebo-controlled trials.
Authors: Yuan Y; Department of Medicine, London Health Science Centre, London, ON, Canada.; Department of Medicine, Division of Gastroenterology, Western University, London, ON, Canada., Jairath V; Department of Medicine, London Health Science Centre, London, ON, Canada.; Department of Medicine, Division of Gastroenterology, Western University, London, ON, Canada.; Department of Epidemiology and Biostatistics, Western University, London, ON, Canada., Hanzel J; Department of Gastroenterology and Hepatology, University Medical Center Ljubljana, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia., Hupe M; Department of Medicine, Division of Gastroenterology, Western University, London, ON, Canada.; Université Grenoble Alpes/Hepato-Gastroenterology and Digestive Oncology Department, CHU Grenoble Alpes/Institute for Advanced Biosciences, CNRS UMR 5309-INSERM U1209, Grenoble, France., Sedano R; Department of Medicine, London Health Science Centre, London, ON, Canada.; Department of Medicine, Division of Gastroenterology, Western University, London, ON, Canada.; Department of Epidemiology and Biostatistics, Western University, London, ON, Canada., Shehab M; Program of Medicine, College of Medicine and Health Sciences, Abdullah Al Salem University, Kuwait City, Kuwait.; Division of Gastroenterology and Hepatology, Department of Medicine, McGill University Health Center, Montreal, QC, Canada.; Department of Medicine, Mubarak Alkabeer Hospital, Jabriya, Kuwait., Nardone OM; Gastroenterology, Department of Public Health, University Federico II of Naples, Naples, Italy., Magro F; CINTESIS@RISE Department, Faculdade de Medicina da Universidade do Porto, Porto, Portugal., Hart A; IBD Unit, Department of Medicine, St Mark's Hospital & Academic Institute, London, United Kingdom., Vuyyuru SK; Department of Medicine, London Health Science Centre, London, ON, Canada.; Department of Medicine, Division of Gastroenterology, Western University, London, ON, Canada.
Source: Inflammatory bowel diseases [Inflamm Bowel Dis] 2026 May 30. Date of Electronic Publication: 2026 May 30.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9508162 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-4844 (Electronic) Linking ISSN: 10780998 NLM ISO Abbreviation: Inflamm Bowel Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1536-4844
DOI:10.1093/ibd/izag099