Urine-derived stem cell extracellular vesicles promote recovery from acute kidney injury in mice and human kidney organoids.

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Title: Urine-derived stem cell extracellular vesicles promote recovery from acute kidney injury in mice and human kidney organoids.
Authors: Qian ES; Department of Medicine, Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, TN 37232 USA.; Tufts University School of Medicine, Boston, MA, 02111., Bejoy J; Department of Medicine, Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, TN 37232 USA., Welch RC; Department of Medicine, Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, TN 37232 USA., Farry JM; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN 37232 USA., Hartert J; Department of Medicine, Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, TN 37232 USA., Cartailler JP; Vanderbilt Center for Stem Cell Biology, Vanderbilt University, Nashville, TN 37232 USA., Gibson-Corley KN; Department of Medicine, Division of Pathology, Microbiology & Immunology, Vanderbilt University Medical Center, Nashville, TN 37232 USA.; Department of Medicine, Comparative Pathology and Research Histology, Vanderbilt University Medical Center, Nashville, TN 37232 USA., Wilson MH; Department of Medicine, Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, TN 37232 USA.; Department of Veterans Affairs, Nashville, TN 37212 USA.; Departments of Pharmacology and Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37232 USA., Woodard LE; Department of Medicine, Division of Nephrology and Hypertension, Vanderbilt University Medical Center, Nashville, TN 37232 USA.; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN 37232 USA.; Vanderbilt Center for Stem Cell Biology, Vanderbilt University, Nashville, TN 37232 USA.; Department of Veterans Affairs, Nashville, TN 37212 USA.
Source: American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2026 Jun 01. Date of Electronic Publication: 2026 Jun 01.
Publication Type: Journal Article
Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901990 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1466 (Electronic) Linking ISSN: 15221466 NLM ISO Abbreviation: Am J Physiol Renal Physiol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1522-1466
DOI:10.1152/ajprenal.00304.2025