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Mammary tumors-derived exosomes induce striatal NF-κB signaling, microglial reactivity, and anxiety/depression-like behaviors.

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Title: Mammary tumors-derived exosomes induce striatal NF-κB signaling, microglial reactivity, and anxiety/depression-like behaviors.
Authors: Han YY; School of Life Sciences, South China Normal University, Guangzhou 510631, China; Department of Radiology, Panyu Central Hospital, Guangzhou 511400, China; Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China. Electronic address: hanyy2025@m.scnu.edu.cn., Wu JC; School of Life Sciences, South China Normal University, Guangzhou 510631, China., Yang HM; Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China., Guo ZW; School of Life Sciences, South China Normal University, Guangzhou 510631, China., Gu CQ; School of Life Sciences, South China Normal University, Guangzhou 510631, China., Deng YW; School of Life Sciences, South China Normal University, Guangzhou 510631, China., Li HD; School of Life Sciences, South China Normal University, Guangzhou 510631, China., Huang MH; School of Life Sciences, South China Normal University, Guangzhou 510631, China., He XP; Department of Radiology, Panyu Central Hospital, Guangzhou 511400, China., Han QJ; Department of Radiology, Panyu Central Hospital, Guangzhou 511400, China., Kong H; School of Life Sciences, South China Normal University, Guangzhou 510631, China., Xu YQ; School of Life Sciences, South China Normal University, Guangzhou 510631, China., Yao J; School of Life Sciences, South China Normal University, Guangzhou 510631, China., Shan PH; School of Life Sciences, South China Normal University, Guangzhou 510631, China., Chen HY; Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China., Wen JY; School of Life Sciences, South China Normal University, Guangzhou 510631, China., Liu DX; Department of Radiology, Panyu Central Hospital, Guangzhou 511400, China., Tang YM; Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China. Electronic address: tangym@mail.sysu.edu.cn., Wang Z; School of Life Sciences, South China Normal University, Guangzhou 510631, China. Electronic address: wangz@m.scnu.edu.cn., Long C; School of Life Sciences, South China Normal University, Guangzhou 510631, China. Electronic address: longcheng@m.scnu.edu.cn.
Source: Brain, behavior, and immunity [Brain Behav Immun] 2026 Jun 01; Vol. 137, pp. 106841. Date of Electronic Publication: 2026 Jun 01.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1090-2139
DOI:10.1016/j.bbi.2026.106841