In silico characterization of bioactive phytochemicals as antivirals targeting the reovirus σ1 protein for inhibiting σ1-mediated host cell entry.

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Title: In silico characterization of bioactive phytochemicals as antivirals targeting the reovirus σ1 protein for inhibiting σ1-mediated host cell entry.
Authors: Dey E; Department of Biochemistry and Biotechnology, University of Science and Technology Chittagong (USTC), Chattogram, Chittagong, Bangladesh.; Bangladesh Bioscience Research Group (BBRG), Chattogram, Chittagong, Bangladesh., Dey S; Department of Biochemistry and Biotechnology, University of Science and Technology Chittagong (USTC), Chattogram, Chittagong, Bangladesh.; Bangladesh Bioscience Research Group (BBRG), Chattogram, Chittagong, Bangladesh., Nandi L; Department of Biochemistry and Biotechnology, University of Science and Technology Chittagong (USTC), Chattogram, Chittagong, Bangladesh.; Bangladesh Bioscience Research Group (BBRG), Chattogram, Chittagong, Bangladesh., Mumit SH; Department of Biochemistry and Biotechnology, University of Science and Technology Chittagong (USTC), Chattogram, Chittagong, Bangladesh.; Bangladesh Bioscience Research Group (BBRG), Chattogram, Chittagong, Bangladesh., Arfat R; Department of Biochemistry and Biotechnology, University of Science and Technology Chittagong (USTC), Chattogram, Chittagong, Bangladesh.; Bangladesh Bioscience Research Group (BBRG), Chattogram, Chittagong, Bangladesh., Saif SR; Department of Biochemistry and Biotechnology, University of Science and Technology Chittagong (USTC), Chattogram, Chittagong, Bangladesh.; Bangladesh Bioscience Research Group (BBRG), Chattogram, Chittagong, Bangladesh., Islam MM; Bangladesh Bioscience Research Group (BBRG), Chattogram, Chittagong, Bangladesh.; Department of Biochemistry and Molecular Biology, Noakhali Science and Technology University (NSTU), Noakhali, Chittagong, Bangladesh.
Source: PloS one [PLoS One] 2026 Jun 03; Vol. 21 (6), pp. e0350009. Date of Electronic Publication: 2026 Jun 03 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1932-6203
DOI:10.1371/journal.pone.0350009