Transcriptional and epigenetic regulation of autophagy: mechanisms, disease relevance and therapeutic opportunities.

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Title: Transcriptional and epigenetic regulation of autophagy: mechanisms, disease relevance and therapeutic opportunities.
Authors: Seo J; Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.; Department of Functional Genomics, University of Science and Technology, Daejeon, Republic of Korea., Park SY; Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.; Department of Functional Genomics, University of Science and Technology, Daejeon, Republic of Korea., Lee DC; Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.; Department of Functional Genomics, University of Science and Technology, Daejeon, Republic of Korea., Yoo W; Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea., Yang YR; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea., Seo HW; Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea., Park JL; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.; Department of Bioscience, University of Science and Technology, Daejeon, Republic of Korea., Joo JY; Department of Pharmacy, College of Pharmacy, Hanyang University, Ansan, Gyeonggi-do, Republic of Korea., Park KC; Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea. kpark@kribb.re.kr.; Department of Functional Genomics, University of Science and Technology, Daejeon, Republic of Korea. kpark@kribb.re.kr., Byun S; Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea. swbyun00@kribb.re.kr.; Department of Functional Genomics, University of Science and Technology, Daejeon, Republic of Korea. swbyun00@kribb.re.kr.
Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 Jun 04; Vol. 11 (1). Date of Electronic Publication: 2026 Jun 04.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2059-3635
DOI:10.1038/s41392-026-02688-3