A multicenter, randomized, parallel-group confirmatory study protocol to evaluate the efficacy of Soft Protector CPC, a novel oral mucosal protectant, in preventing oral mucositis and alleviating pain in patients with breast cancer.
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| Title: | A multicenter, randomized, parallel-group confirmatory study protocol to evaluate the efficacy of Soft Protector CPC, a novel oral mucosal protectant, in preventing oral mucositis and alleviating pain in patients with breast cancer. |
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| Authors: | Omori K; Department of Pathophysiology-Periodontal Science, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan., Furukawa K; Department of Dentistry and Oral Surgery, Shikoku Cancer Center, Ehime, Japan., Usubuchi M; Department of Dentistry, Miyagi Cancer Center, Miyagi, Japan., Hamada T; Department of Dentistry and Oral Surgery, Sagara Hospital, Kagoshima, Japan., Shien T; Department of Breast and Endocrine Surgery, Okayama University Hospital, Okayama, Japan., Yoshida M; Center for Innovative Clinical Medicine, Okayama University Hospital, Okayama, Japan., Nakatsuka Y; Center for Innovative Clinical Medicine, Okayama University Hospital, Okayama, Japan., Hotta K; Center for Innovative Clinical Medicine, Okayama University Hospital, Okayama, Japan., Ibaragi S; Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan., Takashiba S; Department of Pathophysiology-Periodontal Science, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan. |
| Source: | PloS one [PLoS One] 2026 Jun 04; Vol. 21 (6), pp. e0350803. Date of Electronic Publication: 2026 Jun 04 (Print Publication: 2026). |
| Publication Type: | Journal Article; Multicenter Study; Randomized Controlled Trial |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1932-6203 |
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| DOI: | 10.1371/journal.pone.0350803 |
