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Graph Topology Reframes the Coherence of Cell-State Manifold Inference under Heterogeneous Single-Cell Observations.

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Title: Graph Topology Reframes the Coherence of Cell-State Manifold Inference under Heterogeneous Single-Cell Observations.
Authors: Tamura T; Department of Extended Intelligence for Medicine, The Ishii-Ishibashi Laboratory, Keio University School of Medicine and Graduate School of Medicine, Shinjuku, Japan.; Department of Diabetes, Endocrinology, and Metabolism, National Center for Global Health and Medicine, Japan Institute for Health Security, Shinjuku, Japan.; Laboratory of Cancer Cell Systems, National Cancer Center Research Institute, Chuo, Japan., Yamane Y; Department of Extended Intelligence for Medicine, The Ishii-Ishibashi Laboratory, Keio University School of Medicine and Graduate School of Medicine, Shinjuku, Japan., Okano Y; Department of Extended Intelligence for Medicine, The Ishii-Ishibashi Laboratory, Keio University School of Medicine and Graduate School of Medicine, Shinjuku, Japan.; Division of Applied Mathematical Science, RIKEN Center for Interdisciplinary Theoretical and Mathematical Sciences (iTHEMS), RIKEN, Yokohama, Japan., Ishikawa T; Department of Extended Intelligence for Medicine, The Ishii-Ishibashi Laboratory, Keio University School of Medicine and Graduate School of Medicine, Shinjuku, Japan.; Division of Applied Mathematical Science, RIKEN Center for Interdisciplinary Theoretical and Mathematical Sciences (iTHEMS), RIKEN, Yokohama, Japan.; Collective Intelligence Research Laboratory, Graduate School of Arts and Sciences, The University of Tokyo, Meguro, Japan., Sakurada K; Department of Extended Intelligence for Medicine, The Ishii-Ishibashi Laboratory, Keio University School of Medicine and Graduate School of Medicine, Shinjuku, Japan.; Predictive Medicine Special Project, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
Source: Computational and structural biotechnology journal [Comput Struct Biotechnol J] 2026 Jun 03; Vol. 35 (1), pp. 0087. Date of Electronic Publication: 2026 Jun 03 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V. on behalf of Research Network of Computational and Structural Biotechnology Country of Publication: Netherlands NLM ID: 101585369 Publication Model: eCollection Cited Medium: Print ISSN: 2001-0370 (Print) Linking ISSN: 20010370 NLM ISO Abbreviation: Comput Struct Biotechnol J Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2001-0370
DOI:10.34133/csbj.0087