Whole transcriptome analysis of peripheral blood identifies systemic innate immune responses and translation inhibition in subclinical Holstein cattle naturally infected with Mycobacterium avium subsp. paratuberculosis.

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Title: Whole transcriptome analysis of peripheral blood identifies systemic innate immune responses and translation inhibition in subclinical Holstein cattle naturally infected with Mycobacterium avium subsp. paratuberculosis.
Authors: Prado-López A; Department of Animal Science, NEIKER-Basque institute for Agricultural research and Development, Basque Research and Tecnology Alliance (BRTA), Derio, Bizkaia, Spain.; Doctoral Program in Immunology, Microbiology, and Parasitology, Euskal Herriko Unibertsitatea (EHU), Leioa, Bizkaia, Spain., Badia-Bringué G; Department of Animal Science, NEIKER-Basque institute for Agricultural research and Development, Basque Research and Tecnology Alliance (BRTA), Derio, Bizkaia, Spain., Torremocha R; Genomic Unit, Scientific Park of Madrid, Madrid, Spain., Navarro León AI; Centre of Animal Biotechnology, Regional Service of Agricultural Research and Development (SERIDA), Deva, Asturias, Spain., Casais R; Centre of Animal Biotechnology, Regional Service of Agricultural Research and Development (SERIDA), Deva, Asturias, Spain., Alonso-Hearn M; Department of Animal Science, NEIKER-Basque institute for Agricultural research and Development, Basque Research and Tecnology Alliance (BRTA), Derio, Bizkaia, Spain.
Source: Frontiers in immunology [Front Immunol] 2026 May 20; Vol. 17, pp. 1744978. Date of Electronic Publication: 2026 May 20 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2026.1744978