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Ergothioneine-rich water extracts of Hericium erinaceus HE-17 alleviate Alzheimer's disease in mice by regulating oxidative stress, inflammation, and the gut microenvironment.

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Title: Ergothioneine-rich water extracts of Hericium erinaceus HE-17 alleviate Alzheimer's disease in mice by regulating oxidative stress, inflammation, and the gut microenvironment.
Authors: Gao PP; Department of Bioengineering, College of Food Science, South China Agricultural University, Guangzhou, China., Zhou FL; Department of Bioengineering, College of Food Science, South China Agricultural University, Guangzhou, China., Zheng GB; School of Food Science, Guangdong Pharmaceutical University, Zhongshan, China., Liu YL; Key Laboratory of Geriatric Nutrition and Health (Beijing Technology and Business University), Ministry of Education, Beijing Technology and Business University (BTBU), Beijing, China., Cheng SJ; Department of Food Nutrition and Safety/National R&D Center for Chinese Herbal Medicine Processing, School of Engineering, China Pharmaceutical University, Nanjing, China., Ye ZW; Department of Bioengineering, College of Food Science, South China Agricultural University, Guangzhou, China., Liang YT; Department of Bioengineering, College of Food Science, South China Agricultural University, Guangzhou, China., Liu L; Department of Bioengineering, College of Food Science, South China Agricultural University, Guangzhou, China., Guo LQ; Department of Bioengineering, College of Food Science, South China Agricultural University, Guangzhou, China., Lin JF; Department of Bioengineering, College of Food Science, South China Agricultural University, Guangzhou, China.
Source: Frontiers in nutrition [Front Nutr] 2026 May 21; Vol. 13, pp. 1835714. Date of Electronic Publication: 2026 May 21 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S. A Country of Publication: Switzerland NLM ID: 101642264 Publication Model: eCollection Cited Medium: Print ISSN: 2296-861X (Print) Linking ISSN: 2296861X NLM ISO Abbreviation: Front Nutr Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Ergothioneine-rich water extracts of Hericium erinaceus HE-17 alleviate Alzheimer's disease in mice by regulating oxidative stress, inflammation, and the gut microenvironment.
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  Data: <searchLink fieldCode="AU" term="%22Gao+PP%22">Gao PP</searchLink>; Department of Bioengineering, College of Food Science, South China Agricultural University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhou+FL%22">Zhou FL</searchLink>; Department of Bioengineering, College of Food Science, South China Agricultural University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zheng+GB%22">Zheng GB</searchLink>; School of Food Science, Guangdong Pharmaceutical University, Zhongshan, China.<br /><searchLink fieldCode="AU" term="%22Liu+YL%22">Liu YL</searchLink>; Key Laboratory of Geriatric Nutrition and Health (Beijing Technology and Business University), Ministry of Education, Beijing Technology and Business University (BTBU), Beijing, China.<br /><searchLink fieldCode="AU" term="%22Cheng+SJ%22">Cheng SJ</searchLink>; Department of Food Nutrition and Safety/National R&D Center for Chinese Herbal Medicine Processing, School of Engineering, China Pharmaceutical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Ye+ZW%22">Ye ZW</searchLink>; Department of Bioengineering, College of Food Science, South China Agricultural University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Liang+YT%22">Liang YT</searchLink>; Department of Bioengineering, College of Food Science, South China Agricultural University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; Department of Bioengineering, College of Food Science, South China Agricultural University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Guo+LQ%22">Guo LQ</searchLink>; Department of Bioengineering, College of Food Science, South China Agricultural University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Lin+JF%22">Lin JF</searchLink>; Department of Bioengineering, College of Food Science, South China Agricultural University, Guangzhou, China.
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  Data: <searchLink fieldCode="JN" term="%22101642264%22">Frontiers in nutrition</searchLink> [Front Nutr] 2026 May 21; Vol. 13, pp. 1835714. <i>Date of Electronic Publication: </i>2026 May 21 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Media+S%2E+A%22">Frontiers Media S. A </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101642264 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2296-861X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222296861X%22">2296861X </searchLink><i>NLM ISO Abbreviation: </i>Front Nutr <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.3389/fnut.2026.1835714
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        Text: English
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              Text: 2026 May 21
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