Supervised Fine-Tuning of Large Language Models With Chain-of-Thought Reasoning for Pediatric Heart Disease Detection in Unstructured Echocardiogram Reports: Algorithm Development and Validation.

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Title: Supervised Fine-Tuning of Large Language Models With Chain-of-Thought Reasoning for Pediatric Heart Disease Detection in Unstructured Echocardiogram Reports: Algorithm Development and Validation.
Authors: Shi H; Department of Biomedical Engineering, Duke University, 1427 Fitzpatrick Center Box 90281, Durham, NC, 27708, United States, 1 9196695131.; Department of Surgery, Duke University School of Medicine, Durham, NC, United States.; Department of Anesthesiology, Duke University School of Medicine, Durham, NC, United States., Long JB; Department of Anesthesiology, Emory University School of Medicine, Atlanta, GA, United States.; Department of Anesthesiology, Children's Healthcare of Atlanta, Atlanta, GA, United States., Fiedorek MC; Department of Anesthesiology, Emory University School of Medicine, Atlanta, GA, United States.; Department of Anesthesiology, Children's Healthcare of Atlanta, Atlanta, GA, United States., Kilday HD; Department of Anesthesiology, Emory University School of Medicine, Atlanta, GA, United States.; Department of Anesthesiology, Children's Healthcare of Atlanta, Atlanta, GA, United States., Foote HP; Department of Pediatrics, Duke University School of Medicine, Durham, NC, United States., Hornik CP; Department of Pediatrics, Duke University School of Medicine, Durham, NC, United States., Nagori A; Department of Surgery, Duke University School of Medicine, Durham, NC, United States.; Department of Anesthesiology, Duke University School of Medicine, Durham, NC, United States., Xiang Y; Department of Biomedical Engineering, Duke University, 1427 Fitzpatrick Center Box 90281, Durham, NC, 27708, United States, 1 9196695131.; Department of Surgery, Duke University School of Medicine, Durham, NC, United States.; Department of Anesthesiology, Duke University School of Medicine, Durham, NC, United States., Kamaleswaran R; Department of Biomedical Engineering, Duke University, 1427 Fitzpatrick Center Box 90281, Durham, NC, 27708, United States, 1 9196695131.; Department of Surgery, Duke University School of Medicine, Durham, NC, United States.; Department of Anesthesiology, Duke University School of Medicine, Durham, NC, United States.
Source: JMIR formative research [JMIR Form Res] 2026 Jun 08; Vol. 10, pp. e90968. Date of Electronic Publication: 2026 Jun 08.
Publication Type: Journal Article
Journal Info: Publisher: JMIR Publications Country of Publication: Canada NLM ID: 101726394 Publication Model: Electronic Cited Medium: Internet ISSN: 2561-326X (Electronic) Linking ISSN: 2561326X NLM ISO Abbreviation: JMIR Form Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2561-326X
DOI:10.2196/90968