Heart Failure Duration, Cardiac Remodeling, Dysfunction, and Hemodynamic Severity in HFpEF and HFmrEF: Insights From REDUCE LAP-HF II.

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Title: Heart Failure Duration, Cardiac Remodeling, Dysfunction, and Hemodynamic Severity in HFpEF and HFmrEF: Insights From REDUCE LAP-HF II.
Authors: Doi S; Department of Cardiovascular Disease, Mayo Clinic, Rochester, Minnesota, USA., Kazui S; Department of Cardiovascular Disease, Mayo Clinic, Rochester, Minnesota, USA., Akashi N; Department of Cardiovascular Disease, Mayo Clinic, Rochester, Minnesota, USA., Patel RB; Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Komtebedde J; Corvia Medical, Tewksbury, Massachusetts, USA., Mylavarapu U; Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Swarup V; Arizona Heart Rhythm Center, Phoenix, USA., Winkler S; Department of Internal Medicine, BG Klinikum Unfallkrankenhaus, Berlin, Germany., Backhaus SJ; Department of Cardiology, Campus Kerckhoff of the Justus-Liebig-University Giessen, Kerckhoff-Clinic, Bad Nauheim, Germany., Litwin SE; Division of Cardiology, Medical University of South Carolina, Charleston, South Carolina, USA; Ralph H. Johnson Veterans Affairs Health System, Charleston, South Carolina, USA., Mohan RC; Scripps Clinic, La Jolla, California, USA., Kawash R; Division of Cardiovascular Medicine, The Ohio State University, Columbus, Ohio, USA., Sverdlov AL; Cardiovascular Department, John Hunter Hospital, University of Newcastle, New Lambton Heights, Australia., Chung ES; Department of Cardiovascular Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Kaye DM; Department of Cardiology, Alfred Hospital, Melbourne, Australia; School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia; Monash-Alfred-Baker Centre for Cardiovascular Research, Melbourne, Australia; Baker Heart and Diabetes Institute, Melbourne, Australia., Hoendermis E; Department of Cardiology, Centre for Congenital Heart Disease, University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands., Hummel SL; University of Michigan and VA Ann Arbor Health System, Ann Arbor, Michigan, USA., Cikes M; Department of Cardiovascular Diseases, University of Zagreb School of Medicine, University Hospital Centre Zagreb, Zagreb, Croatia., Hayward CS; Department of Heart and Lung Transplantation, St Vincent's Hospital, Sydney, Australia., Starling R; Department of Cardiovascular Medicine, Kaufman Center for Heart Failure Treatment and Recovery, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio, USA., Gupta DK; Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Zirlik A; Department of Internal Medicine, Division of Cardiology, Medical University of Graz, Graz, Austria., McKenzie S; The Prince Charles Hospital, School of Medicine, University of Queensland, Brisbane, Queensland, Australia., Nair A; Department of Cardiology, Kerckhoff-Klinik, Bad Nauheim, Germany., Rieth A; German Center for Cardiovascular, Research, Partner Site RheinMain, Frankfurt AM Main, Germany., Cutlip DE; Baim Clinical Research Institute, Boston, Massachusetts, USA., Solomon SD; Brigham and Women's Hospital, Boston, Massachusetts, USA., van Veldhuisen DJ; University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Leon MB; Departmen of Internal Medicine, Columbia University and Cardiovascular Research Foundation, New York City, New York, USA., Silvestry FE; Division of Cardiovascular Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Shah SJ; Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Borlaug BA; Department of Cardiovascular Disease, Mayo Clinic, Rochester, Minnesota, USA. Electronic address: borlaug.barry@mayo.edu.
Source: JACC. Heart failure [JACC Heart Fail] 2026 Jun 05, pp. 103167. Date of Electronic Publication: 2026 Jun 05.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101598241 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-1787 (Electronic) Linking ISSN: 22131779 NLM ISO Abbreviation: JACC Heart Fail Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2213-1787
DOI:10.1016/j.jchf.2026.103167