Histaminylation alters collagen matrix mechanics and attenuates cardiac fibrosis post-myocardial infarction via mechanotransduction signaling axis.
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| Title: | Histaminylation alters collagen matrix mechanics and attenuates cardiac fibrosis post-myocardial infarction via mechanotransduction signaling axis. |
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| Authors: | Zhu J; Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.; NHC Key Laboratory of Ischemic Heart Diseases, State Key Laboratory of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China., Sun D; Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.; NHC Key Laboratory of Ischemic Heart Diseases, State Key Laboratory of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China., Zeng G; Department of Cardiology, the Second Affiliated Hospital, Hengyang Medical School, Key Laboratory of Heart Failure Prevention & Treatment of Hengyang, Clinical Medicine Research Center of Arteriosclerotic Disease of Hunan Province, University of South China, Hengyang, China., Wu K; Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.; NHC Key Laboratory of Ischemic Heart Diseases, State Key Laboratory of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China., Yang X; Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.; NHC Key Laboratory of Ischemic Heart Diseases, State Key Laboratory of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China., Zhu X; Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.; Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China., Aierken D; Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.; NHC Key Laboratory of Ischemic Heart Diseases, State Key Laboratory of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China., Ding S; Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China.; NHC Key Laboratory of Ischemic Heart Diseases, State Key Laboratory of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China., Wang X; Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China. wang.xiangfei@zs-hospital.sh.cn.; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China. wang.xiangfei@zs-hospital.sh.cn.; NHC Key Laboratory of Ischemic Heart Diseases, State Key Laboratory of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China. wang.xiangfei@zs-hospital.sh.cn., Ge J; Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China. jbge@zs-hospital.sh.cn.; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China. jbge@zs-hospital.sh.cn.; NHC Key Laboratory of Ischemic Heart Diseases, State Key Laboratory of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China. jbge@zs-hospital.sh.cn., Yang X; Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China. yangxiangdong_zs@163.com.; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China. yangxiangdong_zs@163.com.; NHC Key Laboratory of Ischemic Heart Diseases, State Key Laboratory of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China. yangxiangdong_zs@163.com.; Department of Cardiology, the Second Affiliated Hospital, Hengyang Medical School, Key Laboratory of Heart Failure Prevention & Treatment of Hengyang, Clinical Medicine Research Center of Arteriosclerotic Disease of Hunan Province, University of South China, Hengyang, China. yangxiangdong_zs@163.com. |
| Source: | Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 Jun 11; Vol. 11 (1). Date of Electronic Publication: 2026 Jun 11. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2059-3635 |
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| DOI: | 10.1038/s41392-026-02721-5 |
