m6A-modified Mid1 promotes sevoflurane-induced cognitive impairment in neonatal mice by ubiquitin-mediated degradation of Syngap1.

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Title: m6A-modified Mid1 promotes sevoflurane-induced cognitive impairment in neonatal mice by ubiquitin-mediated degradation of Syngap1.
Authors: Shen JJ; Department of Anesthesia, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China., Yang YJ; Department of Anesthesia, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China., Tang YY; Department of Anesthesia, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China., Yan S; Department of Anesthesia, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China., Ying MD; Nanhu Brain-Computer Interface Institute, Hangzhou, Zhejiang Province, China. mying@zju.edu.cn.; Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang Province, China. mying@zju.edu.cn., Chen WH; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences & Forensic Medicine, Hangzhou Medical college, Hangzhou, Zhejiang Province, China. chenwenhu@hmc.edu.cn., Xu LL; Department of Anesthesia, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China. xulili@zju.edu.cn.
Source: Experimental & molecular medicine [Exp Mol Med] 2026 Jun 05. Date of Electronic Publication: 2026 Jun 05.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9607880 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2092-6413 (Electronic) Linking ISSN: 12263613 NLM ISO Abbreviation: Exp Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2092-6413
DOI:10.1038/s12276-026-01747-7