Pathological disruption of CELF2 shuttling causes neuronal hyperactivity, learning deficits, and seizures.

Saved in:
Bibliographic Details
Title: Pathological disruption of CELF2 shuttling causes neuronal hyperactivity, learning deficits, and seizures.
Authors: Hua M; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Canada., Aghanoori MR; Department of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, Canada., MacPherson MJ; Department of Medical Genetics, University of Alberta, Edmonton, Canada., Ren Y; Department of Cell Biology and Anatomy, Cumming School of Medicine, University of Calgary, Calgary, Canada., Siripala SV; Department of Clinical Neuroscience, Cumming School of Medicine, University of Calgary, Calgary, Canada., Yang Y; Department of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, Canada., Or YYY; Department of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, Canada., Nguyen M; Department of Cell Biology and Anatomy, Cumming School of Medicine, University of Calgary, Calgary, Canada., Duba-Kiss R; Department of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, Canada., Feng D; Department of Cell Biology and Anatomy, Cumming School of Medicine, University of Calgary, Calgary, Canada., Williams L; Department of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, Canada., Gafuik CJ; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Canada., Wang G; Center for Neuroscience Research, School of Basic Medical Sciences, Chongqing Medical University, Chongqing, China., Quelin C; Service de Génétique Clinique, Centre de Référence 'Anomalies du Développement et Syndromes Malformatifs' de l'Inter-région Ouest, CHU Rennes Hôpital Sud, Rennes, France., Keren B; Department of Genetics, La Pitié-Salpêtrière Hospital, Assistance Publique Hospital of Paris, Paris, France., Schuhmann S; Institute of Human Genetics, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Vasileiou G; Institute of Human Genetics, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany., Bourgois A; Service de Génétique, Centre Hospitalier Universitaire de Caen, Caen, France., Vitobello A; Université Bourgogne Europe, CHU Dijon Bourgogne, Laboratoire de Génomique Médicale, Centre Neomics, FHU TRANSLAD, Centre de recherche Translationnelle en Médecine moléculaire - Inserm UMR1231, équipe, Dijon, France., Philippe C; Laboratoire de Génétique, Hôpital de Mercy, CHR Metz-Thionville, Metz, France., Stark Z; Victorian Clinical Genetics Services, Murdoch Children's Research Institute, Melbourne, Australia., Leventer RJ; Victorian Clinical Genetics Services, Murdoch Children's Research Institute, Melbourne, Australia., McGillivray G; Victorian Clinical Genetics Services, Murdoch Children's Research Institute, Melbourne, Australia., Tran Mau-Them F; Université Bourgogne Europe, CHU Dijon Bourgogne, Laboratoire de Génomique Médicale, Centre Neomics, FHU TRANSLAD, Centre de recherche Translationnelle en Médecine moléculaire - Inserm UMR1231, équipe, Dijon, France., Tessarech M; Department of Medical Genetics, Angers University Hospital, Angers, France., Prouteau C; Service de Génétique Médicale, CHU d'Angers, Angers, France., Lakeman P; Amsterdam UMC, Department of Human Genetics, University of Amsterdam, Amsterdam, Netherlands., Motazacker MM; Amsterdam UMC, Department of Human Genetics, University of Amsterdam, Amsterdam, Netherlands., Latner DR; HudsonAlpha Institute for Biotechnology, Huntsville, United States of America., Caylor RC; Greenwood Genetic Center, Greenwood, United States of America., van Ierland Y; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, Netherlands., Prijoles E; Greenwood Genetic Center, Greenwood, United States of America., Lichty A; Greenwood Genetic Center, Greenwood, United States of America., Theodorou E; Center for Genomic Medicine, Divisions of Pediatric Hematology/Oncology and, Massachusetts General Hospital, Boston, United States of America., Sweetser DA; Center for Genomic Medicine, Divisions of Pediatric Hematology/Oncology and, Massachusetts General Hospital, Boston, United States of America., Steel E; Clinical Genetics, Great Ormond Street Hospital, London, United Kingdom., Cobben J; Section of Genomics and Genetics, Imperial College London, London, United Kingdom., Dasouki MJ; Department of Medical Genetics & Genomics, AdventHealth Genomics & Personalized Health at Orlando, Orlando, United States of America., Calame DG; Section of Pediatric Neurology and Developmental Neurosciences, Department , Baylor College of Medicine, Houston, United States of America., Isidor B; Nantes Université, CHU de Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Cogné B; Nantes Université, CHU de Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France., Kesler M; Department of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, Canada., Rackel B; Department of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, Canada., Clark I; Department of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, Canada., Kurrasch DM; Department of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, Canada., Teskey GC; Department of Cell Biology and Anatomy, Cumming School of Medicine, University of Calgary, Calgary, Canada., Ellis J; Department of Molecular Genetics, University of Toronto, Toronto, Canada., He G; Center for Neuroscience Research, School of Basic Medical Sciences, Chongqing Medical University, Chongqing, China., Ryan SD; Department of Clinical Neuroscience, Cumming School of Medicine, University of Calgary, Calgary, Canada., Mahoney DJ; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Canada., Innes AM; Department of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, Canada., Epp JR; Department of Cell Biology and Anatomy, Cumming School of Medicine, University of Calgary, Calgary, Canada., Yang G; Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Canada.
Source: The Journal of clinical investigation [J Clin Invest] 2026 Jun 11. Date of Electronic Publication: 2026 Jun 11.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1558-8238
DOI:10.1172/JCI199698