Anti-Inflammatory Potential of 1-Aryl-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinolines: Structure-Activity Relationship and COX-2 Binding.

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Title: Anti-Inflammatory Potential of 1-Aryl-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinolines: Structure-Activity Relationship and COX-2 Binding.
Authors: Azamatov AA; Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, M. Ulugbek Str 77, Tashkent 100170, Uzbekistan., Tursunkhodzhaeva FM; Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, M. Ulugbek Str 77, Tashkent 100170, Uzbekistan., Zhurakulov SN; Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, M. Ulugbek Str 77, Tashkent 100170, Uzbekistan., Boboev ZD; Faculty of Pharmacy and Chemistry, Alfraganus University, Yuqori Qoraqamish Str. 2a, Tashkent 100190, Uzbekistan., Kuchimov KF; Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, M. Ulugbek Str 77, Tashkent 100170, Uzbekistan., Aytmuratova UK; Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, M. Ulugbek Str 77, Tashkent 100170, Uzbekistan., Ortikov IS; Faculty of Pharmacy and Chemistry, Alfraganus University, Yuqori Qoraqamish Str. 2a, Tashkent 100190, Uzbekistan., Abdurazakova RS; Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, M. Ulugbek Str 77, Tashkent 100170, Uzbekistan., Vinogradova VI; Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, M. Ulugbek Str 77, Tashkent 100170, Uzbekistan., Abdullaev IZ; Institute of Bioorganic Chemistry, Academy of Sciences of the Republic of Uzbekistan, M. Ulugbek Str 87, Tashkent 100143, Uzbekistan., Gayibov UG; Institute of Bioorganic Chemistry, Academy of Sciences of the Republic of Uzbekistan, M. Ulugbek Str 87, Tashkent 100143, Uzbekistan.
Source: Molecules (Basel, Switzerland) [Molecules] 2026 Jun 04; Vol. 31 (11). Date of Electronic Publication: 2026 Jun 04.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1420-3049
DOI:10.3390/molecules31111956