Anchusa azurea enhances cisplatin efficacy in oral and bone cancers through IL-17 and TNF-α pathway modulation: a metabolomic and network pharmacology approach.
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| Title: | Anchusa azurea enhances cisplatin efficacy in oral and bone cancers through IL-17 and TNF-α pathway modulation: a metabolomic and network pharmacology approach. |
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| Authors: | Fahim SA; Department of Biochemistry, School of Pharmacy, Newgiza University (NGU), Newgiza, km 22 Cairo-Alexandria Desert Road, Giza, 12577, Egypt. sallyatef@hotmail.com., El-Haddad AE; Department of Pharmacognosy, Faculty of Pharmacy, October 6 University, Giza, 12585, Egypt., Moustafa RI; Microbial Biotechnology Department, Biotechnology Research Institute , National Research Centre, Dokki, P.O. Box 12622, Cairo, Egypt.; Department of Microbiology, School of Pharmacy, Newgiza University (NGU), , Newgiza, km 22 Cairo-Alexandria Desert Road, Giza, 12577, Egypt., Ali SO; Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt., Sharaky M; Cancer Biology Department, National Cancer Institute, Cairo University, Cairo, Egypt., El Sherazy NH; Department of Clinical Pharmacy, School of Pharmacy, Newgiza University (NGU), Km 22 Cairo-Alexandria Desert Road, P.O. Box 12577, Newgiza, Giza, Egypt.; Department of Clinical pharmacy, Cairo University Hospitals, Cairo university, Cairo, Egypt., Elsherbiny AA; Department of Biochemistry, School of Pharmacy, Newgiza University (NGU), Newgiza, km 22 Cairo-Alexandria Desert Road, Giza, 12577, Egypt., Nabawy AY; Microbial Biotechnology Department, Biotechnology Research Institute , National Research Centre, Dokki, P.O. Box 12622, Cairo, Egypt., Elwakil AA; School of Pharmacy, Newgiza University (NGU), Newgiza, km 22 Cairo- Alexandria Desert Road, Giza, 12577, Egypt., Esam HA; School of Pharmacy, Newgiza University (NGU), Newgiza, km 22 Cairo- Alexandria Desert Road, Giza, 12577, Egypt., Emad S; School of Pharmacy, Newgiza University (NGU), Newgiza, km 22 Cairo- Alexandria Desert Road, Giza, 12577, Egypt., Abdelrahman M; School of Pharmacy, Newgiza University (NGU), Newgiza, km 22 Cairo- Alexandria Desert Road, Giza, 12577, Egypt., Ayman M; School of Pharmacy, Newgiza University (NGU), Newgiza, km 22 Cairo- Alexandria Desert Road, Giza, 12577, Egypt., Soliman HAH; School of Pharmacy, Newgiza University (NGU), Newgiza, km 22 Cairo- Alexandria Desert Road, Giza, 12577, Egypt., El-Deeb EM; Pharmacognosy Department, Faculty of Pharmacy and drug technology, Egyptian Chinese University, Cairo, 11771, Egypt., Saadeldeen AM; Department of Pharmacognosy, School of Pharmacy, Newgiza University (NGU), Newgiza, km 22 Cairo-Alexandria Desert Road, Giza, 12577, Egypt. |
| Source: | Scientific reports [Sci Rep] 2026 Jun 13; Vol. 16 (1). Date of Electronic Publication: 2026 Jun 13. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-026-56489-3 |
