Pancreatic islet α cell function and proliferation require the arginine transporter SLC7A2.

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Bibliographic Details
Title: Pancreatic islet α cell function and proliferation require the arginine transporter SLC7A2.
Authors: Spears E; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Biology, Belmont University, Nashville, Tennessee, USA., Stanley JE; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, Tennessee, USA., Shou M; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Yin L; Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, Tennessee, USA., Li X; Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, Tennessee, USA., Dai C; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Bradley A; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Sellick K; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Poffenberger G; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Coate KC; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, Tennessee, USA., Shrestha S; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Schornack AMR; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Shepard T; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, Tennessee, USA., Wimalarathne M; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Jenkins R; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Sloop KW; Diabetes and Complications, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Wilson KT; Division of Gastroenterology, Hepatology & Nutrition, Department of Medicine.; Department of Pathology, Microbiology & Immunology.; Center for Mucosal Inflammation & Cancer; and.; Program in Cancer Biology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.; Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, USA., Attie AD; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA., Keller MP; Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA., Chen W; Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, Tennessee, USA., Powers AC; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, Tennessee, USA.; Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, USA., Dean ED; Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, Tennessee, USA.
Source: The Journal of clinical investigation [J Clin Invest] 2026 Jun 15; Vol. 136 (12). Date of Electronic Publication: 2026 Jun 15 (Print Publication: 2026).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1558-8238
DOI:10.1172/JCI173913