2''-O-galloylhyperin as a novel adjuvant to reduce imipenem resistance in multidrug-resistant Pseudomonas aeruginosa: transcriptome-based mechanism of iron homeostasis disruption.

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Title: 2''-O-galloylhyperin as a novel adjuvant to reduce imipenem resistance in multidrug-resistant Pseudomonas aeruginosa: transcriptome-based mechanism of iron homeostasis disruption.
Authors: Zheng L; School of Biological and Food Engineering, Huanghuai University, Zhumadian, 463000, China., Lu GJ; Key Laboratory of Jilin Province for Zoonoses Prevention and Control, State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Changchun, Jilin, 130000, China., Wang ZX; Key Laboratory of Jilin Province for Zoonoses Prevention and Control, State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Changchun, Jilin, 130000, China., Guo XJ; Key Laboratory of Jilin Province for Zoonoses Prevention and Control, State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Changchun, Jilin, 130000, China., Wang Z; School of Biological and Food Engineering, Huanghuai University, Zhumadian, 463000, China., Shao ZY; School of Biological and Food Engineering, Huanghuai University, Zhumadian, 463000, China., Wang YT; School of Biological and Food Engineering, Huanghuai University, Zhumadian, 463000, China., Jiang HB; School of Biological and Food Engineering, Huanghuai University, Zhumadian, 463000, China., Chen ST; School of Biological and Food Engineering, Huanghuai University, Zhumadian, 463000, China., Wang FY; Key Laboratory of Jilin Province for Zoonoses Prevention and Control, State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Changchun, Jilin, 130000, China.; School and Hospital of Stomatology, Jilin University, Jilin, 130021, China., Li J; Qinghai Center for Animal Disease Prevention and Control, Xining, 810003, China., Lin YQ; Qinghai Center for Animal Disease Prevention and Control, Xining, 810003, China., Zheng SS; Qinghai Center for Animal Disease Prevention and Control, Xining, 810003, China., Lu GH; School of Biological and Food Engineering, Huanghuai University, Zhumadian, 463000, China. 380335460@qq.com., Qi JF; School of Biological and Food Engineering, Huanghuai University, Zhumadian, 463000, China. 1243377523@qq.com., Zhu LW; Key Laboratory of Jilin Province for Zoonoses Prevention and Control, State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Changchun, Jilin, 130000, China. lingweiz@163.com.
Source: BMC microbiology [BMC Microbiol] 2026 Jun 16. Date of Electronic Publication: 2026 Jun 16.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100966981 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-2180 (Electronic) Linking ISSN: 14712180 NLM ISO Abbreviation: BMC Microbiol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1471-2180
DOI:10.1186/s12866-026-05247-6