Severe renal toxicity following adjuvant envafolimab in a patient with ultra-hypermutated (POLE) stage II colorectal cancer: a case report.

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Title: Severe renal toxicity following adjuvant envafolimab in a patient with ultra-hypermutated (POLE) stage II colorectal cancer: a case report.
Authors: Gao Z; Department of Gastroenterology, Shandong Provincial Hospital, Shandong University, Jinan, China.; Department of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China., Zhang C; Department of Gastroenterology, Shandong Provincial Hospital, Shandong University, Jinan, China.; Department of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China., Fang Z; Department of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China., Liu J; Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China., Shang L; Department of Gastroenterology, Shandong Provincial Hospital, Shandong University, Jinan, China.; Department of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China., Li L; Department of Gastroenterology, Shandong Provincial Hospital, Shandong University, Jinan, China.; Department of Gastrointestinal Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Source: AME case reports [AME Case Rep] 2026 Mar 20; Vol. 10, pp. 92. Date of Electronic Publication: 2026 Mar 20 (Print Publication: 2026).
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: AME Publishing Company Country of Publication: China NLM ID: 101730832 Publication Model: eCollection Cited Medium: Internet ISSN: 2523-1995 (Electronic) Linking ISSN: 25231995 NLM ISO Abbreviation: AME Case Rep Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2523-1995
DOI:10.21037/acr-2025-268