Virion display reveals MD-1 as an endogenous agonist for the orphan receptor GPRC5B.
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| Title: | Virion display reveals MD-1 as an endogenous agonist for the orphan receptor GPRC5B. |
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| Authors: | Johansen E; Department of Physiology, Pharmacology and Therapeutics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Syu GD; Department of Physiology, Pharmacology and Therapeutics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan, Taiwan., Wan Z; Center for Bioelectronics and Biosensors, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA., Sarver DC; Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Center for Metabolism and Obesity Research, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Ding M; Department of Physiology, Pharmacology and Therapeutics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Dong X; Solomon H. Snyder Department of Neuroscience, Department of Neurosurgery, Center for Sensory Biology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA., Wang S; Center for Bioelectronics and Biosensors, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.; School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ 85287, USA., Wong GW; Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Center for Metabolism and Obesity Research, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Zhu H; Department of Physiology, Pharmacology and Therapeutics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. |
| Source: | Science signaling [Sci Signal] 2026 Jun 16; Vol. 19 (942), pp. eadr8554. Date of Electronic Publication: 2026 Jun 16. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1937-9145 |
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| DOI: | 10.1126/scisignal.adr8554 |