The LTI-01-2001 phase 2a trial of intrapleural LTI-01 in patients with infected, non-draining pleural effusions.

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Title: The LTI-01-2001 phase 2a trial of intrapleural LTI-01 in patients with infected, non-draining pleural effusions.
Authors: Lamb CR; Lahey Hospital and Medical Center, Pulmonary and Critical Care Medicine, Burlington, USA., Akulian J; Division of Pulmonary Diseases and Critical Care Medicine, University of North Carolina, Chapel Hill, USA., Musani A; Pulmonary and Sleep Medicine, Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra University, New York, USA., Shojaee S; Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt Medical Center, Nashville, USA., Chen A; Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis, USA., Kurman J; Division of Pulmonary & Critical Care, Medical College of Wisconsin, Milwaukee, USA., Jani P; Interventional Pulmonology, UT Houston and Memorial Hermann-Texas Medical Center, Houston, USA., Senitko M; Division of Pulmonary, Critical Care and Sleep Medicine, University of Mississippi Medical Center, Jackson, USA., Ahmad D; Interventional Pulmonology, Division of Pulmonary, Sleep and Critical Care Medicine, Fox Chase Cancer Center Lewis Katz School of Medicine at Temple University, Philadelphia, USA., Wahidi M; Division of Pulmonary and Critical Care, Northwestern University Feinberg School of Medicine, Chicago, USA., Ansari S; Intermountain Health LDS Hospital, Salt Lake City, USA., Abu-Hijleh M; Division of Pulmonary and Critical Care Medicine, Interventional Pulmonology, UT Southwestern Medical Center, Dallas, USA., Ma KC; Pulmonary, Allergy and Critical Care, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, USA., Puchalski J; Department of Pulmonology, Physicians Alliance of Connecticut (PACT), Guilford, USA., Yarmus L; Interventional Pulmonology, the Johns Hopkins University School of Medicine, Baltimore, USA., Kheir F; Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, USA., Maldonado F; Division of Allery, Pulmonary and Critical Care Medicine, Vanderbilt University, Nashville, USA., Cheng G; Interventional Pulmonology, The University of California San Diego, San Diego, USA., Alvarado C; Department of Epidemiology and Biostatistics, School of Medicine, The University of Teas at Tyler, Tyler, USA., Karan SP; Department of Epidemiology and Biostatistics, School of Medicine, The University of Teas at Tyler, Tyler, USA., Windsor B; Rein Therapeutics, Inc., Austin, USA., Rahman NM; Oxford University Hospitals Oxford Respiratory Trials Unit NHS Trust, Oxford, UK., Shoemaker S; Nicosof LLC, Erie, USA., Idell S; Department of Cellular and Molecular Biology, School of Medicine, The University of Texas at Tyler, Routes 271 and 155, Tyler, TX, 75708, USA. Steven.idell@uthct.edu.
Source: Respiratory research [Respir Res] 2026 Jun 17. Date of Electronic Publication: 2026 Jun 17.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101090633 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1465-993X (Electronic) Linking ISSN: 14659921 NLM ISO Abbreviation: Respir Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1465-993X
DOI:10.1186/s12931-026-03782-4