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Genetic variation at the IL-18-137C>G is associated with poor sepsis prognosis and enhanced inflammatory responses: a multicenter hospital-based study.

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Title: Genetic variation at the IL-18-137C>G is associated with poor sepsis prognosis and enhanced inflammatory responses: a multicenter hospital-based study.
Authors: Li Z; Jinan University, Guangzhou, Guangdong, China.; The Intensive Care Unit, The Second Affiliated Hospital, Guangdong Medical University, Zhanjiang, Guangdong, China., Gu W; Jinan University, Guangzhou, Guangdong, China., Liu L; The Intensive Care Unit, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong, China.; The Intensive Care Unit, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China., Li J; The Intensive Care Unit, Jieyang People's Hospital, Jieyang, Guangdong, China., Zhang M; The Intensive Care Unit, Jieyang People's Hospital, Jieyang, Guangdong, China., Yang W; The Intensive Care Unit, Jieyang People's Hospital, Jieyang, Guangdong, China., Yang M; The Intensive Care Unit, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong, China., Zhang J; The Intensive Care Unit, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.; The Intensive Care Unit, Jieyang People's Hospital, Jieyang, Guangdong, China., Zhong H; The Intensive Care Unit, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.; The Intensive Care Unit, Jieyang People's Hospital, Jieyang, Guangdong, China., Liu Y; The Intensive Care Unit, Jieyang People's Hospital, Jieyang, Guangdong, China., He J; The Intensive Care Unit, Jieyang People's Hospital, Jieyang, Guangdong, China., Yin H; Jinan University, Guangzhou, Guangdong, China., Shao Y; Jinan University, Guangzhou, Guangdong, China.; The Intensive Care Unit, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong, China.; The Intensive Care Unit, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Source: Frontiers in genetics [Front Genet] 2026 Jun 03; Vol. 17, pp. 1820930. Date of Electronic Publication: 2026 Jun 03 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101560621 Publication Model: eCollection Cited Medium: Print ISSN: 1664-8021 (Print) Linking ISSN: 16648021 NLM ISO Abbreviation: Front Genet Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Jinan University, Guangzhou, Guangdong, China.; The Intensive Care Unit, The Second Affiliated Hospital, Guangdong Medical University, Zhanjiang, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Gu+W%22">Gu W</searchLink>; Jinan University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; The Intensive Care Unit, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong, China.; The Intensive Care Unit, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; The Intensive Care Unit, Jieyang People's Hospital, Jieyang, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Zhang+M%22">Zhang M</searchLink>; The Intensive Care Unit, Jieyang People's Hospital, Jieyang, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Yang+W%22">Yang W</searchLink>; The Intensive Care Unit, Jieyang People's Hospital, Jieyang, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Yang+M%22">Yang M</searchLink>; The Intensive Care Unit, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; The Intensive Care Unit, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.; The Intensive Care Unit, Jieyang People's Hospital, Jieyang, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Zhong+H%22">Zhong H</searchLink>; The Intensive Care Unit, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.; The Intensive Care Unit, Jieyang People's Hospital, Jieyang, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; The Intensive Care Unit, Jieyang People's Hospital, Jieyang, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22He+J%22">He J</searchLink>; The Intensive Care Unit, Jieyang People's Hospital, Jieyang, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Yin+H%22">Yin H</searchLink>; Jinan University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Shao+Y%22">Shao Y</searchLink>; Jinan University, Guangzhou, Guangdong, China.; The Intensive Care Unit, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, Guangdong, China.; The Intensive Care Unit, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
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  Data: <searchLink fieldCode="JN" term="%22101560621%22">Frontiers in genetics</searchLink> [Front Genet] 2026 Jun 03; Vol. 17, pp. 1820930. <i>Date of Electronic Publication: </i>2026 Jun 03 (<i>Print Publication: </i>2026).
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              Text: 2026 Jun 03
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