Chemo-omic pipeline enables discovery of prion synaptotoxic pathways and inhibitory drugs.
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| Title: | Chemo-omic pipeline enables discovery of prion synaptotoxic pathways and inhibitory drugs. |
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| Authors: | Le NTT; Department of Biochemistry and Cell Biology, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, United States of America., Mercer RCC; Department of Biochemistry and Cell Biology, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, United States of America., Fang C; Department of Biochemistry and Cell Biology, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, United States of America., Sundaravadivelu A; Department of Biochemistry and Cell Biology, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, United States of America., Labadorf AT; Bioinformatics Program, Boston University, Boston, Massachusetts, United States of America., Lin W; Department of Pharmacology, Physiology and Biophysics, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, United States of America., Kwan J; Department of Biochemistry and Cell Biology, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, United States of America., Blum B; Department of Biochemistry and Cell Biology, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, United States of America., Emili A; Department of Biochemistry and Cell Biology, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, United States of America., Harris DA; Department of Biochemistry and Cell Biology, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts, United States of America. |
| Source: | PLoS pathogens [PLoS Pathog] 2026 Jun 18; Vol. 22 (6), pp. e1014314. Date of Electronic Publication: 2026 Jun 18 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1553-7374 |
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| DOI: | 10.1371/journal.ppat.1014314 |
