Structure of the NAT10 acetyltransferase and mechanism of tRNA acetylation.

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Title: Structure of the NAT10 acetyltransferase and mechanism of tRNA acetylation.
Authors: Zhou M; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA.; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Thalalla Gamage S; Chemical Biology Laboratory, National Cancer Institute, Frederick, MD, USA., Tran KA; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Epigenetics Institute, Perelman School of Medicine, University of Philadelphia, Philadelphia, PA, USA., Bartee D; Chemical Biology Laboratory, National Cancer Institute, Frederick, MD, USA., Wei X; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Biochemistry and Biophysics Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Guangzhou National Laboratory, Guangzhou, China., Yin B; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA.; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Berger S; Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Epigenetics Institute, Perelman School of Medicine, University of Philadelphia, Philadelphia, PA, USA.; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA.; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Meier JL; Chemical Biology Laboratory, National Cancer Institute, Frederick, MD, USA. jordan.meier@nih.gov., Marmorstein R; Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA. marmor@upenn.edu.; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. marmor@upenn.edu.; Epigenetics Institute, Perelman School of Medicine, University of Philadelphia, Philadelphia, PA, USA. marmor@upenn.edu.; Department of Biochemistry and Biophysics Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. marmor@upenn.edu.
Source: Nature communications [Nat Commun] 2026 Jun 20. Date of Electronic Publication: 2026 Jun 20.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-026-74222-6