pH-responsive in situ antigen capture and cytosolic delivery synergize to elicit robust systemic antitumor immunity.

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Title: pH-responsive in situ antigen capture and cytosolic delivery synergize to elicit robust systemic antitumor immunity.
Authors: Bi Z; Key Laboratory of Marine Drugs (Ocean University of China), Chinese Ministry of Education, and School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.; Laboratory for Marine Drugs and Bioproducts, Qingdao Marine Science and Technology Center, 266237, Qingdao, China.; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Zhang S; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Jin G; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Yang Z; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Lin S; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Wang L; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Yu B; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Wang L; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Su Y; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Xiang S; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Xiang X; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Lv L; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Lao T; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Zhou J; Key Laboratory of Marine Drugs (Ocean University of China), Chinese Ministry of Education, and School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.; Laboratory for Marine Drugs and Bioproducts, Qingdao Marine Science and Technology Center, 266237, Qingdao, China., Lv S; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China. lvshixian@pku.edu.cn., Rong X; Key Laboratory of Marine Drugs (Ocean University of China), Chinese Ministry of Education, and School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China. rongxiaozhi@ouc.edu.cn.; Laboratory for Marine Drugs and Bioproducts, Qingdao Marine Science and Technology Center, 266237, Qingdao, China. rongxiaozhi@ouc.edu.cn.
Source: Journal of nanobiotechnology [J Nanobiotechnology] 2026 Jun 19. Date of Electronic Publication: 2026 Jun 19.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-3155 (Electronic) Linking ISSN: 14773155 NLM ISO Abbreviation: J Nanobiotechnology Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1477-3155
DOI:10.1186/s12951-026-04698-3