pH-responsive in situ antigen capture and cytosolic delivery synergize to elicit robust systemic antitumor immunity.

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Title: pH-responsive in situ antigen capture and cytosolic delivery synergize to elicit robust systemic antitumor immunity.
Authors: Bi Z; Key Laboratory of Marine Drugs (Ocean University of China), Chinese Ministry of Education, and School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.; Laboratory for Marine Drugs and Bioproducts, Qingdao Marine Science and Technology Center, 266237, Qingdao, China.; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Zhang S; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Jin G; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Yang Z; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Lin S; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Wang L; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Yu B; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Wang L; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Su Y; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Xiang S; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Xiang X; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Lv L; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Lao T; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China., Zhou J; Key Laboratory of Marine Drugs (Ocean University of China), Chinese Ministry of Education, and School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.; Laboratory for Marine Drugs and Bioproducts, Qingdao Marine Science and Technology Center, 266237, Qingdao, China., Lv S; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China. lvshixian@pku.edu.cn., Rong X; Key Laboratory of Marine Drugs (Ocean University of China), Chinese Ministry of Education, and School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China. rongxiaozhi@ouc.edu.cn.; Laboratory for Marine Drugs and Bioproducts, Qingdao Marine Science and Technology Center, 266237, Qingdao, China. rongxiaozhi@ouc.edu.cn.
Source: Journal of nanobiotechnology [J Nanobiotechnology] 2026 Jun 19. Date of Electronic Publication: 2026 Jun 19.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-3155 (Electronic) Linking ISSN: 14773155 NLM ISO Abbreviation: J Nanobiotechnology Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: pH-responsive in situ antigen capture and cytosolic delivery synergize to elicit robust systemic antitumor immunity.
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  Data: <searchLink fieldCode="AU" term="%22Bi+Z%22">Bi Z</searchLink>; Key Laboratory of Marine Drugs (Ocean University of China), Chinese Ministry of Education, and School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.; Laboratory for Marine Drugs and Bioproducts, Qingdao Marine Science and Technology Center, 266237, Qingdao, China.; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China.<br /><searchLink fieldCode="AU" term="%22Jin+G%22">Jin G</searchLink>; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China.<br /><searchLink fieldCode="AU" term="%22Yang+Z%22">Yang Z</searchLink>; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China.<br /><searchLink fieldCode="AU" term="%22Lin+S%22">Lin S</searchLink>; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China.<br /><searchLink fieldCode="AU" term="%22Yu+B%22">Yu B</searchLink>; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China.<br /><searchLink fieldCode="AU" term="%22Su+Y%22">Su Y</searchLink>; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China.<br /><searchLink fieldCode="AU" term="%22Xiang+S%22">Xiang S</searchLink>; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China.<br /><searchLink fieldCode="AU" term="%22Xiang+X%22">Xiang X</searchLink>; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China.<br /><searchLink fieldCode="AU" term="%22Lv+L%22">Lv L</searchLink>; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China.<br /><searchLink fieldCode="AU" term="%22Lao+T%22">Lao T</searchLink>; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China.<br /><searchLink fieldCode="AU" term="%22Zhou+J%22">Zhou J</searchLink>; Key Laboratory of Marine Drugs (Ocean University of China), Chinese Ministry of Education, and School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China.; Laboratory for Marine Drugs and Bioproducts, Qingdao Marine Science and Technology Center, 266237, Qingdao, China.<br /><searchLink fieldCode="AU" term="%22Lv+S%22">Lv S</searchLink>; School of Materials Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Peking University, Beijing, 100871, China. lvshixian@pku.edu.cn.<br /><searchLink fieldCode="AU" term="%22Rong+X%22">Rong X</searchLink>; Key Laboratory of Marine Drugs (Ocean University of China), Chinese Ministry of Education, and School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003, China. rongxiaozhi@ouc.edu.cn.; Laboratory for Marine Drugs and Bioproducts, Qingdao Marine Science and Technology Center, 266237, Qingdao, China. rongxiaozhi@ouc.edu.cn.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101152208 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1477-3155 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214773155%22">14773155 </searchLink><i>NLM ISO Abbreviation: </i>J Nanobiotechnology <i>Subsets: </i>MEDLINE
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1186/s12951-026-04698-3
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      – Code: eng
        Text: English
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      – TitleFull: pH-responsive in situ antigen capture and cytosolic delivery synergize to elicit robust systemic antitumor immunity.
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              Text: 2026 Jun 19
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