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Direct Access to Chiral Tertiary Alcohols via Copper-Catalyzed Enantioconvergent O-Alkylation of Water with Racemic α-Tertiary Haloamides.

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Title: Direct Access to Chiral Tertiary Alcohols via Copper-Catalyzed Enantioconvergent O-Alkylation of Water with Racemic α-Tertiary Haloamides.
Authors: Zhang JY; Department of Chemistry, School of Sciences and Guangdong Provincial Key Laboratory of Mathematical and Neural Dynamical Systems, Great Bay University, Dongguan 523000, China.; New Cornerstone Science Laboratory, Shenzhen Grubbs Institute, Department of Chemistry, and Guangming Advanced Research Institute, Southern University of Science and Technology, Shenzhen 518055, China., Huang PJ; Department of Chemistry, School of Sciences and Guangdong Provincial Key Laboratory of Mathematical and Neural Dynamical Systems, Great Bay University, Dongguan 523000, China.; New Cornerstone Science Laboratory, Shenzhen Grubbs Institute, Department of Chemistry, and Guangming Advanced Research Institute, Southern University of Science and Technology, Shenzhen 518055, China., Chen SY; Department of Chemistry, School of Sciences and Guangdong Provincial Key Laboratory of Mathematical and Neural Dynamical Systems, Great Bay University, Dongguan 523000, China., Luan C; New Cornerstone Science Laboratory, Shenzhen Grubbs Institute, Department of Chemistry, and Guangming Advanced Research Institute, Southern University of Science and Technology, Shenzhen 518055, China., Gu QS; New Cornerstone Science Laboratory, Shenzhen Grubbs Institute, Department of Chemistry, and Guangming Advanced Research Institute, Southern University of Science and Technology, Shenzhen 518055, China.; Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis, Southern University of Science and Technology, Shenzhen 518055, China., Wang B; New Cornerstone Science Laboratory, Shenzhen Grubbs Institute, Department of Chemistry, and Guangming Advanced Research Institute, Southern University of Science and Technology, Shenzhen 518055, China., Zhang YF; New Cornerstone Science Laboratory, Shenzhen Grubbs Institute, Department of Chemistry, and Guangming Advanced Research Institute, Southern University of Science and Technology, Shenzhen 518055, China., Yang CJ; Department of Chemistry, School of Sciences and Guangdong Provincial Key Laboratory of Mathematical and Neural Dynamical Systems, Great Bay University, Dongguan 523000, China., Chen JJ; New Cornerstone Science Laboratory, Shenzhen Grubbs Institute, Department of Chemistry, and Guangming Advanced Research Institute, Southern University of Science and Technology, Shenzhen 518055, China., Liu XY; New Cornerstone Science Laboratory, Shenzhen Grubbs Institute, Department of Chemistry, and Guangming Advanced Research Institute, Southern University of Science and Technology, Shenzhen 518055, China.
Source: Journal of the American Chemical Society [J Am Chem Soc] 2026 Jun 21. Date of Electronic Publication: 2026 Jun 21.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Direct Access to Chiral Tertiary Alcohols via Copper-Catalyzed Enantioconvergent O-Alkylation of Water with Racemic α-Tertiary Haloamides.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+JY%22">Zhang JY</searchLink>; Department of Chemistry, School of Sciences and Guangdong Provincial Key Laboratory of Mathematical and Neural Dynamical Systems, Great Bay University, Dongguan 523000, China.; New Cornerstone Science Laboratory, Shenzhen Grubbs Institute, Department of Chemistry, and Guangming Advanced Research Institute, Southern University of Science and Technology, Shenzhen 518055, China.<br /><searchLink fieldCode="AU" term="%22Huang+PJ%22">Huang PJ</searchLink>; Department of Chemistry, School of Sciences and Guangdong Provincial Key Laboratory of Mathematical and Neural Dynamical Systems, Great Bay University, Dongguan 523000, China.; New Cornerstone Science Laboratory, Shenzhen Grubbs Institute, Department of Chemistry, and Guangming Advanced Research Institute, Southern University of Science and Technology, Shenzhen 518055, China.<br /><searchLink fieldCode="AU" term="%22Chen+SY%22">Chen SY</searchLink>; Department of Chemistry, School of Sciences and Guangdong Provincial Key Laboratory of Mathematical and Neural Dynamical Systems, Great Bay University, Dongguan 523000, China.<br /><searchLink fieldCode="AU" term="%22Luan+C%22">Luan C</searchLink>; New Cornerstone Science Laboratory, Shenzhen Grubbs Institute, Department of Chemistry, and Guangming Advanced Research Institute, Southern University of Science and Technology, Shenzhen 518055, China.<br /><searchLink fieldCode="AU" term="%22Gu+QS%22">Gu QS</searchLink>; New Cornerstone Science Laboratory, Shenzhen Grubbs Institute, Department of Chemistry, and Guangming Advanced Research Institute, Southern University of Science and Technology, Shenzhen 518055, China.; Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis, Southern University of Science and Technology, Shenzhen 518055, China.<br /><searchLink fieldCode="AU" term="%22Wang+B%22">Wang B</searchLink>; New Cornerstone Science Laboratory, Shenzhen Grubbs Institute, Department of Chemistry, and Guangming Advanced Research Institute, Southern University of Science and Technology, Shenzhen 518055, China.<br /><searchLink fieldCode="AU" term="%22Zhang+YF%22">Zhang YF</searchLink>; New Cornerstone Science Laboratory, Shenzhen Grubbs Institute, Department of Chemistry, and Guangming Advanced Research Institute, Southern University of Science and Technology, Shenzhen 518055, China.<br /><searchLink fieldCode="AU" term="%22Yang+CJ%22">Yang CJ</searchLink>; Department of Chemistry, School of Sciences and Guangdong Provincial Key Laboratory of Mathematical and Neural Dynamical Systems, Great Bay University, Dongguan 523000, China.<br /><searchLink fieldCode="AU" term="%22Chen+JJ%22">Chen JJ</searchLink>; New Cornerstone Science Laboratory, Shenzhen Grubbs Institute, Department of Chemistry, and Guangming Advanced Research Institute, Southern University of Science and Technology, Shenzhen 518055, China.<br /><searchLink fieldCode="AU" term="%22Liu+XY%22">Liu XY</searchLink>; New Cornerstone Science Laboratory, Shenzhen Grubbs Institute, Department of Chemistry, and Guangming Advanced Research Institute, Southern University of Science and Technology, Shenzhen 518055, China.
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        Value: 10.1021/jacs.6c08724
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        Text: English
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      – TitleFull: Direct Access to Chiral Tertiary Alcohols via Copper-Catalyzed Enantioconvergent O-Alkylation of Water with Racemic α-Tertiary Haloamides.
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            – D: 21
              M: 06
              Text: 2026 Jun 21
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