Metformin attenuates diabetic osteoporosis via the miR-21 mediated Mef2c/Sost pathway.
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| Title: | Metformin attenuates diabetic osteoporosis via the miR-21 mediated Mef2c/Sost pathway. |
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| Authors: | Liu L; Department of Geriatrics, Second Hospital of Tianjin Medical University, Tianjin, China., Xu J; NHC Key Lab of Hormones and Development and Tianjin Key Lab of Metabolic Diseases, Tianjin Medical University Chu Hsien-I Memorial Hospital & Institute of Endocrinology, Tianjin, China., Zheng H; Endocrinology Department, TEDA International Cardiovascular Hospital, Tianjin, China., Li XC; NHC Key Lab of Hormones and Development and Tianjin Key Lab of Metabolic Diseases, Tianjin Medical University Chu Hsien-I Memorial Hospital & Institute of Endocrinology, Tianjin, China., Gao ZA; NHC Key Lab of Hormones and Development and Tianjin Key Lab of Metabolic Diseases, Tianjin Medical University Chu Hsien-I Memorial Hospital & Institute of Endocrinology, Tianjin, China., Meng C; Department of Nephrology, Kidney Disease Medical Center, General Hospital, Tianjin Medical University, National Key Clinical Specialty, Tianjin Key Medical Discipline, Tianjin, China., Pan C; NHC Key Lab of Hormones and Development and Tianjin Key Lab of Metabolic Diseases, Tianjin Medical University Chu Hsien-I Memorial Hospital & Institute of Endocrinology, Tianjin, China., Yang JH; Guangdong Provincial Key Laboratory of Autophagy and Major Chronic Non-communicable Diseases, Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China., Chang BC; NHC Key Lab of Hormones and Development and Tianjin Key Lab of Metabolic Diseases, Tianjin Medical University Chu Hsien-I Memorial Hospital & Institute of Endocrinology, Tianjin, China. |
| Source: | Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2026 Jun 05; Vol. 17, pp. 1841140. Date of Electronic Publication: 2026 Jun 05 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-2392 |
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| DOI: | 10.3389/fendo.2026.1841140 |
