Targeting STAT3 in systemic lupus erythematosus and lupus nephritis: mechanisms, therapeutic advances, and structure-informed perspectives.

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Title: Targeting STAT3 in systemic lupus erythematosus and lupus nephritis: mechanisms, therapeutic advances, and structure-informed perspectives.
Authors: Yi F; Hangzhou Clinical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Tu X; Hangzhou Clinical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.; Hangzhou Hospital of Traditional Chinese Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Jin R; Hangzhou Clinical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Zhou J; Hangzhou Clinical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Li Y; Department of Nephrology (Key Laboratory of Kidney Disease Prevention and Control Technology), Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang, China., Liao H; Hangzhou Clinical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China., Xu W; Department of Nephrology (Key Laboratory of Kidney Disease Prevention and Control Technology), Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang, China., Yuan Y; Department of Nephrology (Key Laboratory of Kidney Disease Prevention and Control Technology), Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang, China., Wu M; Department of Nephrology (Key Laboratory of Kidney Disease Prevention and Control Technology), Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang, China., Bi P; Department of Nephrology (Key Laboratory of Kidney Disease Prevention and Control Technology), Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang, China., Yin J; Department of Nephrology (Key Laboratory of Kidney Disease Prevention and Control Technology), Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang, China.
Source: Frontiers in pharmacology [Front Pharmacol] 2026 Jun 04; Vol. 17, pp. 1854754. Date of Electronic Publication: 2026 Jun 04 (Print Publication: 2026).
Publication Type: Journal Article; Review
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:1663-9812
DOI:10.3389/fphar.2026.1854754