Donepezil ameliorates fatigue and depression in PASC patients with HHV-6B SITH-1-induced acetylcholine deficiency.

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Title: Donepezil ameliorates fatigue and depression in PASC patients with HHV-6B SITH-1-induced acetylcholine deficiency.
Authors: Oka N; Department of Virology, The Jikei University School of Medicine, Tokyo, Japan., Nakamura K; Department of Critical Care Medicine, Yokohama City University Hospital, Yokohama, Kanagawa, Japan., Hirahata K; Hirahata Clinic, Tokyo, Japan., Ishii A; Department of Virology, The Jikei University School of Medicine, Tokyo, Japan., Yamakawa K; Department of Emergency and Critical Care Medicine, Osaka Medical and Pharmaceutical University, Takatsuki, Osaka, Japan., Ie K; Department of General Internal Medicine, Kawasaki Municipal Tama Hospital, Kawasaki, Kanagawa, Japan., Goto T; TXP Medical Co. Ltd., Tokyo, Japan., Shimada K; Department of Virology, The Jikei University School of Medicine, Tokyo, Japan., Fujitani S; Department of Emergency and Critical Care Medicine, St. Marianna University School of Medicine, Kawasaki, Kanagawa, Japan., Kondo K; Department of Fatigue Science, The Jikei University School of Medicine, Tokyo, Japan.
Source: Frontiers in pharmacology [Front Pharmacol] 2026 Jun 04; Vol. 17, pp. 1807203. Date of Electronic Publication: 2026 Jun 04 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:1663-9812
DOI:10.3389/fphar.2026.1807203