Memory regulatory T cells reprogram into protective TFH cell-like effectors in recurrent malaria.

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Title: Memory regulatory T cells reprogram into protective TFH cell-like effectors in recurrent malaria.
Authors: Charles-Chess NAE; Department of Cellular Biology, University of Georgia, Athens, GA, USA.; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, USA., Ruberto AA; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, USA.; Institute of Bioinformatics, University of Georgia, Athens, GA, USA.; Department of Biomedical Sciences, Florida State University, Tallahassee, FL, USA., Bowers C; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, USA., Schmidt-Silva C; Department of Cellular Biology, University of Georgia, Athens, GA, USA.; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, USA., Obeng-Adjei N; Malaria Infection Biology and Immunity Section, Laboratory of Immunogenetics, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, US National Institutes of Health, Rockville, MD, USA., Hansen MR; Department of Cellular Biology, University of Georgia, Athens, GA, USA., B R Prasad D; Department of Cellular Biology, University of Georgia, Athens, GA, USA., Rosenberg A; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, USA., Traore B; Mali International Centre of Excellence in Research, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali., Klonowski KD; Department of Cellular Biology, University of Georgia, Athens, GA, USA., Crompton PD; Malaria Infection Biology and Immunity Section, Laboratory of Immunogenetics, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, US National Institutes of Health, Rockville, MD, USA., Kurup SP; Department of Cellular Biology, University of Georgia, Athens, GA, USA. samar@uga.edu.; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA, USA. samar@uga.edu.
Source: Nature immunology [Nat Immunol] 2026 Jun 22. Date of Electronic Publication: 2026 Jun 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1529-2916
DOI:10.1038/s41590-026-02537-z