Interim Estimated Effectiveness of 2025-2026 COVID-19 Vaccines in Adults Using a Test-Negative Design.

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Title: Interim Estimated Effectiveness of 2025-2026 COVID-19 Vaccines in Adults Using a Test-Negative Design.
Authors: Wiegand RE; National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia., Chickery S; Westat, Bethesda, Maryland., Yang DH; Westat, Bethesda, Maryland., Ball SW; Westat, Bethesda, Maryland., DeSilva MB; HealthPartners Institute, Minneapolis, Minnesota., Dascomb K; Division of Infectious Diseases and Clinical Epidemiology, Intermountain Health, Salt Lake City, Utah., Irving SA; Kaiser Permanente Center for Health Research, Portland, Oregon., Natarajan K; Department of Biomedical Informatics, Columbia University Irving Medical Center, New York, New York., Klein NP; Kaiser Permanente Vaccine Study Center, Kaiser Permanente Northern California Division of Research, Oakland., Grannis SJ; Center for Biomedical Informatics, Regenstrief Institute, Indianapolis, Indiana.; Department of Family Medicine, School of Medicine, Indiana University, Indianapolis., Ong TC; School of Medicine, University of Colorado Anschutz Medical Campus, Aurora., Rowley EAK; Westat, Bethesda, Maryland., Yates A; Westat, Bethesda, Maryland., Zhuang Y; Westat, Bethesda, Maryland., Wilson S; Westat, Bethesda, Maryland., McEvoy CE; HealthPartners Institute, Minneapolis, Minnesota., Essien IJ; HealthPartners Institute, Minneapolis, Minnesota., Akinsete OO; HealthPartners Institute, Minneapolis, Minnesota., Naleway AL; Kaiser Permanente Center for Health Research, Portland, Oregon., Koppolu P; Kaiser Permanente Center for Health Research, Portland, Oregon., Zerbo O; Kaiser Permanente Vaccine Study Center, Kaiser Permanente Northern California Division of Research, Oakland., Hansen JR; Kaiser Permanente Vaccine Study Center, Kaiser Permanente Northern California Division of Research, Oakland., Jacobson KB; Kaiser Permanente Vaccine Study Center, Kaiser Permanente Northern California Division of Research, Oakland., Block L; Kaiser Permanente Vaccine Study Center, Kaiser Permanente Northern California Division of Research, Oakland., Dixon BE; Center for Biomedical Informatics, Regenstrief Institute, Indianapolis, Indiana.; Department of Health Policy and Management, Richard M. Fairbanks School of Public Health, Indiana University, Indianapolis., Duszynski T; Center for Biomedical Informatics, Regenstrief Institute, Indianapolis, Indiana.; Department of Epidemiology, Richard M. Fairbanks School of Public Health, Indiana University, Indianapolis., Rogerson C; Center for Biomedical Informatics, Regenstrief Institute, Indianapolis, Indiana.; Department of Pediatrics, School of Medicine, Indiana University, Indianapolis., Barron MA; School of Medicine, University of Colorado Anschutz Medical Campus, Aurora., Chavez C; School of Medicine, University of Colorado Anschutz Medical Campus, Aurora., Mak J; National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia., Ciesla AA; National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.; Eagle Health Analytics, San Antonio, Texas., Godfrey M; National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia., Kautz A; National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.; General Dynamics Information Technology, Atlanta, Georgia., Najdowski M; National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.; Eagle Health Analytics, San Antonio, Texas., Link-Gelles R; National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.; US Public Health Service Commissioned Corps, Rockville, Maryland., DeCuir J; National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia., Payne AB; National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Source: JAMA network open [JAMA Netw Open] 2026 Jun 01; Vol. 9 (6), pp. e2625152. Date of Electronic Publication: 2026 Jun 01.
Publication Type: Journal Article
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101729235 Publication Model: Electronic Cited Medium: Internet ISSN: 2574-3805 (Electronic) Linking ISSN: 25743805 NLM ISO Abbreviation: JAMA Netw Open Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2574-3805
DOI:10.1001/jamanetworkopen.2026.25152