Identifying potential drug targets for physical and cognitive frailty: an integrative analysis of CHARLS cohort, mendelian randomization, and gene colocalization.

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Title: Identifying potential drug targets for physical and cognitive frailty: an integrative analysis of CHARLS cohort, mendelian randomization, and gene colocalization.
Authors: Liu W; Department of Cadre Health Care and Geriatrics, The Second Qilu Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, China., Zhao J; Department of Spine Surgery, The Second Qilu Hospital of Shandong University, Jinan, Shandong, China., Liu ZQ; Department of Cadre Health Care and Geriatrics, The Second Qilu Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, China., Sun XD; Department of Cadre Health Care and Geriatrics, The Second Qilu Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, China., Dong YY; Department of Cadre Health Care and Geriatrics, The Second Qilu Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, China., Meng YJ; Department of Cadre Health Care and Geriatrics, The Second Qilu Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, China., Jiang WD; Department of Cadre Health Care and Geriatrics, The Second Qilu Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, China., Liu Z; Department of Cadre Health Care and Geriatrics, The Second Qilu Hospital of Shandong University, 247 Beiyuan Street, Jinan, 250033, Shandong, China. liuzhen1204@163.com.
Source: Biogerontology [Biogerontology] 2026 Jun 23; Vol. 27 (4). Date of Electronic Publication: 2026 Jun 23.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Academic Country of Publication: Netherlands NLM ID: 100930043 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-6768 (Electronic) Linking ISSN: 13895729 NLM ISO Abbreviation: Biogerontology Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1573-6768
DOI:10.1007/s10522-026-10466-5