Real-world, multi-omics validation of the clinical relevance of molecular taxonomy for myelodysplastic syndromes (MDS).

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Title: Real-world, multi-omics validation of the clinical relevance of molecular taxonomy for myelodysplastic syndromes (MDS).
Authors: Maggioni G; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Todisco G; IRCCS Humanitas Research Hospital Rozzano Milan Italy.; Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy., Sauta E; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Lanino L; Hematology Section, Department of Internal Medicine Yale School of Medicine New Haven USA., Ball S; Vanderbilt Ingram Cancer Center and Vanderbilt University School of Medicine Nashville Tennessee USA., Bewersdorf JP; Hematology Section, Department of Internal Medicine Yale School of Medicine New Haven USA., Kewan T; Hematology Section, Department of Internal Medicine Yale School of Medicine New Haven USA., Al Ali NH; Department of Malignant Hematology H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA., Fenaux P; Hôpital Saint-Louis Université Paris Cité Paris France., Platzbecker U; Universitätsklinikum Carl Gustav Carus Dresden Germany., Santini V; University of Florence Florence Italy., Xie Z; Department of Malignant Hematology H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA., Brunner AM; Leukemia Program, Massachusetts General Hospital Cancer Center Harvard Medical School Boston Massachusetts USA., Kuykendall AT; Department of Malignant Hematology H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA., Bennett JM; University of Rochester Medical Center Rochester New York USA., Buckstein R; Odette Cancer Centre Sunnybrook Health Sciences Centre Toronto Ontario Canada., Bejar R; University of California San Diego La Jolla California USA., Carraway HE; Leukemia Program, Taussig Cancer Institute Cleveland Clinic Cleveland Ohio USA., DeZern AE; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University Baltimore Maryland USA., Griffiths EA; Roswell Park Comprehensive Cancer Center Buffalo New York USA., Halene S; Hematology Section, Department of Internal Medicine Yale School of Medicine New Haven USA., Hasserjian RP; Massachusetts General Hospital Boston Massachusetts USA., List AF; Precision BioSciences Durham North Carolina USA., Loghavi S; Department of Hematopathology The University of Texas MD Anderson Cancer Center Houston Texas USA., Odenike O; University of Chicago Medicine and University of Chicago Comprehensive Cancer Center Chicago Illinois USA., Padron E; Department of Malignant Hematology H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA., Patnaik MM; Department of Internal Medicine, Division of Hematology Mayo Clinic Rochester Minnesota USA., Roboz GJ; New York-Presbyterian/Weill Cornell Medicine New York New York USA., Stahl M; Hematology Section, Department of Internal Medicine Yale School of Medicine New Haven USA., Sekeres MA; Sylvester Comprehensive Cancer Center University of Miami Miami Florida USA., Steensma DP; Ajax Therapeutics Cambridge Massachusetts USA., Savona MR; Vanderbilt Ingram Cancer Center and Vanderbilt University School of Medicine Nashville Tennessee USA., Taylor J; Sylvester Comprehensive Cancer Center University of Miami Miami Florida USA., Xu ML; Department of Pathology & Laboratory Medicine Yale School of Medicine New Haven Connecticut USA., Sallman DA; Department of Malignant Hematology H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA., Nimer SD; Sylvester Comprehensive Cancer Center University of Miami Miami Florida USA., Hourigan CS; Virginia Tech FBRI Cancer Research Center Washington District of Columbia USA., Wei AH; Department of Haematology Peter MacCallum Cancer Centre, Melbourne Victoria Australia., Campagna A; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Ubezio M; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Riva E; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Ventura D; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Pinocchio N; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Zampini M; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Buizza A; IRCCS Humanitas Research Hospital Rozzano Milan Italy.; Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy., Russo A; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Pesce F; Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy., D'Amico S; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Asti G; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Delleani M; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Travaglino E; IRCCS Policlinico San Matteo Pavia Italy., Tentori CA; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Ferrari I; IRCCS Humanitas Research Hospital Rozzano Milan Italy.; Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy., Crespi A; IRCCS Humanitas Research Hospital Rozzano Milan Italy.; Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy., Figini G; IRCCS Humanitas Research Hospital Rozzano Milan Italy.; Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy., Di Matteo M; IRCCS Humanitas Research Hospital Rozzano Milan Italy.; Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy., Brindisi M; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Manes N; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Milanesi C; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Crisafulli L; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Ficara F; IRCCS Humanitas Research Hospital Rozzano Milan Italy., Castellani G; Department of Medical and Surgical Sciences-DIMEC University of Bologna Bologna Italy., Borate UM; Department of Internal Medicine, Division of Hematology The Ohio State University Columbus Ohio USA., Efficace F; Italian Group for Adult Haematologic Diseases (GIMEMA) Rome Italy., Gore SD; Division of Cancer Prevention National Cancer Institute Rockville Maryland USA., Kim TK; Vanderbilt Ingram Cancer Center and Vanderbilt University School of Medicine Nashville Tennessee USA., Diez-Campelo M; Department of Hematology Hospital Universitario de Salamanca Salamanca Spain., van de Loosdrecht AA; Department of Hematology VU University Medical Center-Cancer Center Amsterdam Netherlands., Daver N; Department of Leukemia The University of Texas MD Anderson Cancer Center Houston Texas USA., Rozman M; Hospital Clínic Barcelona Barcelona Spain., Orfao A; Department of Hematology Hospital Universitario de Salamanca Salamanca Spain., Wang SA; Department of Hematopathology The University of Texas MD Anderson Cancer Center Houston Texas USA., Foucar K; University of New Mexico Albuquerque New Mexico USA., Iastrebner M; Sanatorio Sagrado Corazón Buenos Aires Argentina., Scheinberg P; Hospital A Beneficência Portuguesa de São Paulo Sao Paulo Brazil., Miyazaki Y; Atomic Bomb Disease Institute Nagasaki University Nagasaki Japan., Madanat YF; Division of Hematology and Oncology UT Southwestern Dallas Texas USA., Al-Kali A; Department of Internal Medicine, Division of Hematology Mayo Clinic Rochester Minnesota USA., Mittelmann M; Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine Tel Aviv University Tel-Aviv Israel., Cluzeau T; Nice University Hospital Nice France., Ades L; Hôpital Saint-Louis Université Paris Cité Paris France., Germing U; Department of Hematology, Oncology, and Clinical Immunology Heinrich-Heine-University Düsseldorf Germany., Garcia-Manero G; Department of Leukemia The University of Texas MD Anderson Cancer Center Houston Texas USA., Kordasti S; Department of Haematology Guy's Hospital & Comprehensive Cancer Centre, King's College London UK., Haferlach T; MLL Munich Leukemia Laboratory Munich Germany., Zeidan AM; Hematology Section, Department of Internal Medicine Yale School of Medicine New Haven USA., Komrokji RS; Department of Malignant Hematology H. Lee Moffitt Cancer Center and Research Institute Tampa Florida USA., Della Porta MG; IRCCS Humanitas Research Hospital Rozzano Milan Italy.; Department of Biomedical Sciences Humanitas University Pieve Emanuele Milan Italy.
Corporate Authors: An international study on behalf of GenoMed4all, Synthema, and icMDS consortia
Source: HemaSphere [Hemasphere] 2026 Jun 22; Vol. 10 (6), pp. e70406. Date of Electronic Publication: 2026 Jun 22 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101740619 Publication Model: eCollection Cited Medium: Internet ISSN: 2572-9241 (Electronic) Linking ISSN: 25729241 NLM ISO Abbreviation: Hemasphere Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2572-9241
DOI:10.1002/hem3.70406