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Actin derangement and increased Piezo1 activity in Ras-transformed cells promote cyclic stretch-induced cell detachment and apoptosis.

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Title: Actin derangement and increased Piezo1 activity in Ras-transformed cells promote cyclic stretch-induced cell detachment and apoptosis.
Authors: Wong TY; International Center for Wound Repair and Regeneration, National Cheng Kung University, No.1 University Road, Tainan City, 701, Taiwan.; Cross College Elite Program, National Cheng Kung University, No.1 University Road, Tainan City, 701, Taiwan., Lee LW; International Center for Wound Repair and Regeneration, National Cheng Kung University, No.1 University Road, Tainan City, 701, Taiwan.; Department of Physiology, College of Medicine, National Cheng Kung University, No.1 University Road, Tainan City, 701, Taiwan., Lee GH; International Center for Wound Repair and Regeneration, National Cheng Kung University, No.1 University Road, Tainan City, 701, Taiwan., Huang JY; International Center for Wound Repair and Regeneration, National Cheng Kung University, No.1 University Road, Tainan City, 701, Taiwan., Tang MJ; International Center for Wound Repair and Regeneration, National Cheng Kung University, No.1 University Road, Tainan City, 701, Taiwan. mjtang1@mail.ncku.edu.tw.; Department of Physiology, College of Medicine, National Cheng Kung University, No.1 University Road, Tainan City, 701, Taiwan. mjtang1@mail.ncku.edu.tw.
Source: Scientific reports [Sci Rep] 2026 Jun 26. Date of Electronic Publication: 2026 Jun 26.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Actin derangement and increased Piezo1 activity in Ras-transformed cells promote cyclic stretch-induced cell detachment and apoptosis.
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  Data: <searchLink fieldCode="AU" term="%22Wong+TY%22">Wong TY</searchLink>; International Center for Wound Repair and Regeneration, National Cheng Kung University, No.1 University Road, Tainan City, 701, Taiwan.; Cross College Elite Program, National Cheng Kung University, No.1 University Road, Tainan City, 701, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+LW%22">Lee LW</searchLink>; International Center for Wound Repair and Regeneration, National Cheng Kung University, No.1 University Road, Tainan City, 701, Taiwan.; Department of Physiology, College of Medicine, National Cheng Kung University, No.1 University Road, Tainan City, 701, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+GH%22">Lee GH</searchLink>; International Center for Wound Repair and Regeneration, National Cheng Kung University, No.1 University Road, Tainan City, 701, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+JY%22">Huang JY</searchLink>; International Center for Wound Repair and Regeneration, National Cheng Kung University, No.1 University Road, Tainan City, 701, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tang+MJ%22">Tang MJ</searchLink>; International Center for Wound Repair and Regeneration, National Cheng Kung University, No.1 University Road, Tainan City, 701, Taiwan. mjtang1@mail.ncku.edu.tw.; Department of Physiology, College of Medicine, National Cheng Kung University, No.1 University Road, Tainan City, 701, Taiwan. mjtang1@mail.ncku.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2026 Jun 26. <i>Date of Electronic Publication: </i>2026 Jun 26.
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      – Type: doi
        Value: 10.1038/s41598-026-59854-4
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        Text: English
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      – TitleFull: Actin derangement and increased Piezo1 activity in Ras-transformed cells promote cyclic stretch-induced cell detachment and apoptosis.
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            NameFull: Wong TY
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            NameFull: Lee LW
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            – D: 26
              M: 06
              Text: 2026 Jun 26
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              Y: 2026
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