Early binding of anti-amyloid antibodies to CAA drives complement activation, inflammation and ARIA in mice.

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Title: Early binding of anti-amyloid antibodies to CAA drives complement activation, inflammation and ARIA in mice.
Authors: Bathini P; Brigham and Women's Hospital, Boston, MA, USA. pbathini@bwh.harvard.edu.; Harvard Medical School, Boston, MA, USA. pbathini@bwh.harvard.edu., Schilling S; Fraunhofer Institute for Cell Therapy and Immunology, Halle (Saale), Germany.; Anhalt University of Applied Sciences, Köthen, Germany., Rahfeld JU; Fraunhofer Institute for Cell Therapy and Immunology, Halle (Saale), Germany.; Anhalt University of Applied Sciences, Köthen, Germany., Holtzman DM; Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA., Saido TC; RIKEN Center for Brain Science, Wako, Japan., Lemere CA; Brigham and Women's Hospital, Boston, MA, USA. clemere@bwh.harvard.edu.; Harvard Medical School, Boston, MA, USA. clemere@bwh.harvard.edu.
Source: Molecular neurodegeneration [Mol Neurodegener] 2026 Jun 26. Date of Electronic Publication: 2026 Jun 26.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-1326 (Electronic) Linking ISSN: 17501326 NLM ISO Abbreviation: Mol Neurodegener Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1750-1326
DOI:10.1186/s13024-026-00965-x