Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research
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| Title: | Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research |
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| Description: | This book explains how to determine sample size for studies with correlated outcomes, which are widely implemented in medical, epidemiological, and behavioral studies. For clustered studies, the authors provide sample size formulas that account for variable cluster sizes and within-cluster correlation. For longitudinal studies, they present sample size formulas that account for within-subject correlation among repeated measurements and various missing data patterns. For multiple levels of clustering, the authors describe how randomization impacts trial administration, analysis, and sample size requirement. |
| Authors: | Chul Ahn, Moonseoung Heo, Song Zhang |
| Resource Type: | eBook. |
| Subjects: | Clinical medicine--Research--Statistical metho, Sampling (Statistics) |
| Categories: | MEDICAL / Biostatistics, MATHEMATICS / Probability & Statistics / General |
| Database: | eBook Collection (EBSCOhost) |
| Abstract: | This book explains how to determine sample size for studies with correlated outcomes, which are widely implemented in medical, epidemiological, and behavioral studies. For clustered studies, the authors provide sample size formulas that account for variable cluster sizes and within-cluster correlation. For longitudinal studies, they present sample size formulas that account for within-subject correlation among repeated measurements and various missing data patterns. For multiple levels of clustering, the authors describe how randomization impacts trial administration, analysis, and sample size requirement. |
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| ISBN: | 9781466556263 9780367575991 9781466556270 9780429097683 9781040059456 |
