No evidence for metabolic syndrome and lipid profile differences in patients suffering from bipolar I disorder with and without suicide attempts.
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| Title: | No evidence for metabolic syndrome and lipid profile differences in patients suffering from bipolar I disorder with and without suicide attempts. |
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| Authors: | Ahmadpanah, Mohammad (AUTHOR), Haghighi, Mohammad (AUTHOR), Jahangard, Leila (AUTHOR), Borzoei, Shiva (AUTHOR), Heshmati, Safora (AUTHOR), Bajoghli, Hafez (AUTHOR), Holsboer-Trachsler, Edith (AUTHOR), Brand, Serge (AUTHOR) |
| Source: | International Journal of Psychiatry in Clinical Practice. Aug2015, Vol. 19 Issue 3, p168-173. 6p. |
| Subjects: | Analysis of variance, Blood pressure measurement, Chi-squared test, High density lipoproteins, Interviewing, Lipids, Low density lipoproteins, Bipolar disorder, Probability theory, Psychiatrists, Suicidal behavior, Metabolic syndrome, Body mass index, Cross-sectional method, Data analysis software, Waist circumference, Descriptive statistics |
| Geographic Terms: | Iran |
| Abstract: | Objective.The aim of the present study was to provide further evidence of (1) metabolic syndrome and blood lipid profile differences between suicide attempting and non-attempting patients with bipolar disorder (BPD) I and to assess these differences (2) as a function of acute depressive or manic phase.Methods.Fifty inpatients (mean age: 36.14 years 48% males) with BPD I took part in the study. After recruitment, patients were clustered in four groups: 13 suicide attempters (SAs) assessed during a manic phase, 12 SAs assessed during a depressive phase, 15 non-SAs assessed during a manic phase, and 10 non-SAs assessed during a depressive phase. Body mass index (BMI), metabolic syndrome, blood pressure, blood lipids (cholesterol, high- and low-density lipids, and triglyceride), and fasting blood sugar were assessed.Results.Neither metabolic syndrome, blood lipid values, fasting blood sugar, nor BMI or blood pressure differed between the SAs and non-SAs, or between patients in an acute manic phase and those in a depressed phase. The overall prevalence of metabolic syndrome was 26.0%.Conclusion. Among patients with BPD I neither the occurrence of metabolic syndrome nor lipid values or fasting blood sugar are reliable biomarkers of suicidal behavior during either acute depressive or manic phase. [ABSTRACT FROM AUTHOR] |
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| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | Objective.The aim of the present study was to provide further evidence of (1) metabolic syndrome and blood lipid profile differences between suicide attempting and non-attempting patients with bipolar disorder (BPD) I and to assess these differences (2) as a function of acute depressive or manic phase.Methods.Fifty inpatients (mean age: 36.14 years 48% males) with BPD I took part in the study. After recruitment, patients were clustered in four groups: 13 suicide attempters (SAs) assessed during a manic phase, 12 SAs assessed during a depressive phase, 15 non-SAs assessed during a manic phase, and 10 non-SAs assessed during a depressive phase. Body mass index (BMI), metabolic syndrome, blood pressure, blood lipids (cholesterol, high- and low-density lipids, and triglyceride), and fasting blood sugar were assessed.Results.Neither metabolic syndrome, blood lipid values, fasting blood sugar, nor BMI or blood pressure differed between the SAs and non-SAs, or between patients in an acute manic phase and those in a depressed phase. The overall prevalence of metabolic syndrome was 26.0%.Conclusion. Among patients with BPD I neither the occurrence of metabolic syndrome nor lipid values or fasting blood sugar are reliable biomarkers of suicidal behavior during either acute depressive or manic phase. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 13651501 |
| DOI: | 10.3109/13651501.2015.1049277 |
