Prescription Stimulants and PTSD Among U.S. Military Service Members.
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| Title: | Prescription Stimulants and PTSD Among U.S. Military Service Members. |
|---|---|
| Authors: | Crum‐Cianflone, Nancy F., Frasco, Melissa A., Armenta, Richard F., Phillips, Christopher J., Horton, Jaime, Ryan, Margaret A. K., Russell, Dale W., LeardMann, Cynthia, Crum-Cianflone, Nancy F (AUTHOR) |
| Source: | Journal of Traumatic Stress. Dec2015, Vol. 28 Issue 6, p585-589. 5p. 2 Charts. |
| Subjects: | Post-traumatic stress disorder, Diseases in military personnel, Drug prescribing, Stimulants, Secondary analysis, Therapeutics, Pharmacokinetics, Diagnosis of post-traumatic stress disorder, Drug therapy, Attention-deficit hyperactivity disorder, Demography, Drugs, Research funding, Military personnel, Psychology of military personnel, Comorbidity, Disease incidence, Central nervous system stimulants, Proportional hazards models |
| Geographic Terms: | United States |
| Abstract: | Posttraumatic stress disorder (PTSD) is a prevalent condition among military service members and civilians who have experienced traumatic events. Stimulant use has been postulated to increase the risk of incident PTSD; however, research in this area is lacking. In this study, the association between receipt of prescription stimulants and PTSD was examined in a secondary analysis among active duty U.S. military members (n = 25,971), participating in the Millennium Cohort Study, who completed a baseline (2001-2003) and two follow-up surveys (between 2004-2008). Prescription stimulant data were obtained from the military Pharmacy Data Transaction Service. PTSD was assessed using the PTSD Checklist-Civilian Version and incident PTSD was defined as meeting the criteria at follow-up among those who did not have a history of PTSD at baseline. Overall, 1,215 (4.7%) persons developed new-onset PTSD during follow-up. Receipt of prescription stimulants were significantly associated with incident PTSD, hazard ratio = 5.09, 95% confidence interval [3.05, 8.50], after adjusting for sociodemographic factors, military characteristics, attention-deficit/hyperactivity disorder, baseline mental and physical health status, deployment experiences, and physical/sexual trauma. Findings suggested that prescription stimulants are associated with incident PTSD among military personnel; these data may inform the underlying pathogenesis of and preventive strategies for PTSD. [ABSTRACT FROM AUTHOR] |
| Copyright of Journal of Traumatic Stress is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 111472995 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Prescription Stimulants and PTSD Among U.S. Military Service Members. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Crum‐Cianflone%2C+Nancy+F%2E%22">Crum‐Cianflone, Nancy F.</searchLink><br /><searchLink fieldCode="AR" term="%22Frasco%2C+Melissa+A%2E%22">Frasco, Melissa A.</searchLink><br /><searchLink fieldCode="AR" term="%22Armenta%2C+Richard+F%2E%22">Armenta, Richard F.</searchLink><br /><searchLink fieldCode="AR" term="%22Phillips%2C+Christopher+J%2E%22">Phillips, Christopher J.</searchLink><br /><searchLink fieldCode="AR" term="%22Horton%2C+Jaime%22">Horton, Jaime</searchLink><br /><searchLink fieldCode="AR" term="%22Ryan%2C+Margaret+A%2E+K%2E%22">Ryan, Margaret A. K.</searchLink><br /><searchLink fieldCode="AR" term="%22Russell%2C+Dale+W%2E%22">Russell, Dale W.</searchLink><br /><searchLink fieldCode="AR" term="%22LeardMann%2C+Cynthia%22">LeardMann, Cynthia</searchLink><br /><searchLink fieldCode="AR" term="%22Crum-Cianflone%2C+Nancy+F%22">Crum-Cianflone, Nancy F</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Journal+of+Traumatic+Stress%22">Journal of Traumatic Stress</searchLink>. Dec2015, Vol. 28 Issue 6, p585-589. 5p. 2 Charts. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Post-traumatic+stress+disorder%22">Post-traumatic stress disorder</searchLink><br /><searchLink fieldCode="DE" term="%22Diseases+in+military+personnel%22">Diseases in military personnel</searchLink><br /><searchLink fieldCode="DE" term="%22Drug+prescribing%22">Drug prescribing</searchLink><br /><searchLink fieldCode="DE" term="%22Stimulants%22">Stimulants</searchLink><br /><searchLink fieldCode="DE" term="%22Secondary+analysis%22">Secondary analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Therapeutics%22">Therapeutics</searchLink><br /><searchLink fieldCode="DE" term="%22Pharmacokinetics%22">Pharmacokinetics</searchLink><br /><searchLink fieldCode="DE" term="%22Diagnosis+of+post-traumatic+stress+disorder%22">Diagnosis of post-traumatic stress disorder</searchLink><br /><searchLink fieldCode="DE" term="%22Drug+therapy%22">Drug therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Attention-deficit+hyperactivity+disorder%22">Attention-deficit hyperactivity disorder</searchLink><br /><searchLink fieldCode="DE" term="%22Demography%22">Demography</searchLink><br /><searchLink fieldCode="DE" term="%22Drugs%22">Drugs</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Military+personnel%22">Military personnel</searchLink><br /><searchLink fieldCode="DE" term="%22Psychology+of+military+personnel%22">Psychology of military personnel</searchLink><br /><searchLink fieldCode="DE" term="%22Comorbidity%22">Comorbidity</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+incidence%22">Disease incidence</searchLink><br /><searchLink fieldCode="DE" term="%22Central+nervous+system+stimulants%22">Central nervous system stimulants</searchLink><br /><searchLink fieldCode="DE" term="%22Proportional+hazards+models%22">Proportional hazards models</searchLink> – Name: SubjectGeographic Label: Geographic Terms Group: Su Data: <searchLink fieldCode="DE" term="%22United+States%22">United States</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Posttraumatic stress disorder (PTSD) is a prevalent condition among military service members and civilians who have experienced traumatic events. Stimulant use has been postulated to increase the risk of incident PTSD; however, research in this area is lacking. In this study, the association between receipt of prescription stimulants and PTSD was examined in a secondary analysis among active duty U.S. military members (n = 25,971), participating in the Millennium Cohort Study, who completed a baseline (2001-2003) and two follow-up surveys (between 2004-2008). Prescription stimulant data were obtained from the military Pharmacy Data Transaction Service. PTSD was assessed using the PTSD Checklist-Civilian Version and incident PTSD was defined as meeting the criteria at follow-up among those who did not have a history of PTSD at baseline. Overall, 1,215 (4.7%) persons developed new-onset PTSD during follow-up. Receipt of prescription stimulants were significantly associated with incident PTSD, hazard ratio = 5.09, 95% confidence interval [3.05, 8.50], after adjusting for sociodemographic factors, military characteristics, attention-deficit/hyperactivity disorder, baseline mental and physical health status, deployment experiences, and physical/sexual trauma. Findings suggested that prescription stimulants are associated with incident PTSD among military personnel; these data may inform the underlying pathogenesis of and preventive strategies for PTSD. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Journal of Traumatic Stress is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/jts.22052 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 5 StartPage: 585 Subjects: – SubjectFull: Post-traumatic stress disorder Type: general – SubjectFull: Diseases in military personnel Type: general – SubjectFull: Drug prescribing Type: general – SubjectFull: Stimulants Type: general – SubjectFull: Secondary analysis Type: general – SubjectFull: Therapeutics Type: general – SubjectFull: Pharmacokinetics Type: general – SubjectFull: Diagnosis of post-traumatic stress disorder Type: general – SubjectFull: Drug therapy Type: general – SubjectFull: Attention-deficit hyperactivity disorder Type: general – SubjectFull: Demography Type: general – SubjectFull: Drugs Type: general – SubjectFull: Research funding Type: general – SubjectFull: Military personnel Type: general – SubjectFull: Psychology of military personnel Type: general – SubjectFull: Comorbidity Type: general – SubjectFull: Disease incidence Type: general – SubjectFull: Central nervous system stimulants Type: general – SubjectFull: Proportional hazards models Type: general – SubjectFull: United States Type: general Titles: – TitleFull: Prescription Stimulants and PTSD Among U.S. Military Service Members. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Crum‐Cianflone, Nancy F. – PersonEntity: Name: NameFull: Frasco, Melissa A. – PersonEntity: Name: NameFull: Armenta, Richard F. – PersonEntity: Name: NameFull: Phillips, Christopher J. – PersonEntity: Name: NameFull: Horton, Jaime – PersonEntity: Name: NameFull: Ryan, Margaret A. K. – PersonEntity: Name: NameFull: Russell, Dale W. – PersonEntity: Name: NameFull: LeardMann, Cynthia – PersonEntity: Name: NameFull: Crum-Cianflone, Nancy F IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: Dec2015 Type: published Y: 2015 Identifiers: – Type: issn-print Value: 08949867 Numbering: – Type: volume Value: 28 – Type: issue Value: 6 Titles: – TitleFull: Journal of Traumatic Stress Type: main |
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