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Course of residual symptoms according to the duration of euthymia in remitted bipolar patients.

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Title: Course of residual symptoms according to the duration of euthymia in remitted bipolar patients.
Authors: Samalin, L., Reinares, M., de Chazeron, I., Torrent, C., Bonnin, C. M., Hidalgo‐Mazzei, D., Murru, A., Pacchiarotti, I., Geoffroy, P. A., Bellivier, F., Llorca, P. M., Vieta, E.
Source: Acta Psychiatrica Scandinavica. Jul2016, Vol. 134 Issue 1, p57-64. 8p.
Subjects: Diagnosis of bipolar disorder, Symptoms, Affective disorders, Psychoses, Bipolar disorder, Diagnosis, Patients
Abstract: Objective Although many studies showed the negative impact of residual symptoms on the course of bipolar disorder ( BD), there is a need to examine potential differences in residual symptoms according to the duration of euthymia in remitted BD patients. Method This was a large cross-sectional study of 525 euthymic BD out-patients. A multivariate analysis of covariance was conducted to compare depressive and manic residual symptoms, sleep disturbances and cognitive complaints among three patient groups on the basis of duration of euthymia (A. 6 months to <1 year; B. 1 year to <3 years; C. 3 years to ≤5 years). Results A significant difference between the three groups was found in residual symptoms [Pillai's Trace: F(8942) = 4.659, P < 0.001]. Tukey post hoc analysis indicated that patients from Group C presented lower residual depressive symptoms, higher sleep quality and better perceived cognitive performance compared with Group A. Group B also presented better sleep and cognitive outcomes than Group A. In addition, Group C showed the lowest incidence of functional impairment. Conclusion This study suggests that the intensity of residual symptoms and functional impairment in remitted BD patients is negatively related to the duration of euthymia. [ABSTRACT FROM AUTHOR]
Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Course of residual symptoms according to the duration of euthymia in remitted bipolar patients.
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Acta+Psychiatrica+Scandinavica%22&quot;&gt;Acta Psychiatrica Scandinavica&lt;/searchLink&gt;. Jul2016, Vol. 134 Issue 1, p57-64. 8p.
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  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Diagnosis+of+bipolar+disorder%22&quot;&gt;Diagnosis of bipolar disorder&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Symptoms%22&quot;&gt;Symptoms&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Affective+disorders%22&quot;&gt;Affective disorders&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Psychoses%22&quot;&gt;Psychoses&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Bipolar+disorder%22&quot;&gt;Bipolar disorder&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Diagnosis%22&quot;&gt;Diagnosis&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Patients%22&quot;&gt;Patients&lt;/searchLink&gt;
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  Data: Objective Although many studies showed the negative impact of residual symptoms on the course of bipolar disorder ( BD), there is a need to examine potential differences in residual symptoms according to the duration of euthymia in remitted BD patients. Method This was a large cross-sectional study of 525 euthymic BD out-patients. A multivariate analysis of covariance was conducted to compare depressive and manic residual symptoms, sleep disturbances and cognitive complaints among three patient groups on the basis of duration of euthymia (A. 6 months to &lt;1 year; B. 1 year to &lt;3 years; C. 3 years to ≤5 years). Results A significant difference between the three groups was found in residual symptoms [Pillai&#39;s Trace: F(8942) = 4.659, P &lt; 0.001]. Tukey post hoc analysis indicated that patients from Group C presented lower residual depressive symptoms, higher sleep quality and better perceived cognitive performance compared with Group A. Group B also presented better sleep and cognitive outcomes than Group A. In addition, Group C showed the lowest incidence of functional impairment. Conclusion This study suggests that the intensity of residual symptoms and functional impairment in remitted BD patients is negatively related to the duration of euthymia. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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