The role of parent and offspring sex on risk for externalizing psychopathology in offspring with parental alcohol use disorder: a national Swedish study.
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| Title: | The role of parent and offspring sex on risk for externalizing psychopathology in offspring with parental alcohol use disorder: a national Swedish study. |
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| Authors: | Long, E. C., Lönn, S. L., Sundquist, J., Sundquist, K., Kendler, K. S. |
| Source: | Social Psychiatry & Psychiatric Epidemiology. Dec2018, Vol. 53 Issue 12, p1381-1389. 9p. |
| Subjects: | Pathological psychology, Children of people with alcoholism, Externalizing behavior, Drug abuse risk factors, Genetics of criminal behavior, Substance abuse & psychology, Alcoholism, Psychology of parents, Questionnaires, Research funding, Sex distribution, Substance abuse, Acquisition of data, Disease prevalence, Children of people with mental illness, Impact of Event Scale, Psychology |
| Geographic Terms: | Sweden |
| Abstract: | |
| Copyright of Social Psychiatry & Psychiatric Epidemiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | <bold>Purpose: </bold>The substantial literature showing that offspring of parents with alcohol use disorder (AUD) is at increased risk for externalizing psychopathology rarely examines the differential effects of parental and offspring sex. This literature also has other important limitations, such as modest sample sizes and use of unrepresentative samples. Using a large, nationwide Swedish sample, we aim to investigate the roles of parental and offspring sex in externalizing psychopathology among offspring with parental AUD.<bold>Methods: </bold>AUD diagnosis and externalizing measures were obtained from national registries. Associations between outcomes and parental AUD were examined using logistic regressions. Parental and offspring sex effects were examined with interaction terms.<bold>Results: </bold>Risks for externalizing disorders were increased in sons and daughters with parental AUD, with significant differences between sons and daughters for criminal behavior; maternal AUD had a greater impact than paternal AUD (regardless of offspring sex), but having two parents with AUD increased risk for all outcomes substantially more than having one parent; and maternal AUD increased risk of drug abuse for daughters more than sons, while paternal AUD increased risk of AUD and criminal behavior for sons more than daughters.<bold>Conclusions: </bold>Offspring of parents with AUD are at increased risk for externalizing psychopathology. Maternal and paternal AUD differentially affected sons' vs. daughters' risks for AUD, drug abuse, and criminal behavior. The transmission of psychopathology within the externalizing spectrum appears to have sex-specific elements. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 09337954 |
| DOI: | 10.1007/s00127-018-1563-5 |
