Cellular mechanism of renin release.
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| Title: | Cellular mechanism of renin release. |
|---|---|
| Authors: | Schweda, F., Kurtz, A. |
| Source: | Acta Physiologica Scandinavica. Aug2004, Vol. 181 Issue 4, p383-390. 8p. |
| Subjects: | Calcium, Cyclic adenylic acid, Exocytosis, Renin, Kidneys, Physiology |
| Abstract: | In this review we aim to give a comprehensive overview over the current knowledge of the cellular control of renin release. We hereby focus on the inhibitory effects of calcium on the exocytosis of renin. After a short introduction into general aspects of the regulation of renin release, including a brief summary on the role of the second messengers cAMP and cGMP, we will discuss parts of the literature on the effects of calcium on the renin system together with recent studies from our laboratory, investigating putative calcium influx and extrusion pathways of juxtaglomerular cells. Finally, as the precise mechanisms by which calcium inhibits the exocytosis of renin are far from being understood, we will present some hypotheses on the intracellular events being involved in the suppression of renin release by calcium. [ABSTRACT FROM AUTHOR] |
| Copyright of Acta Physiologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 13952699 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Cellular mechanism of renin release. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Schweda%2C+F%2E%22">Schweda, F.</searchLink><br /><searchLink fieldCode="AR" term="%22Kurtz%2C+A%2E%22">Kurtz, A.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Acta+Physiologica+Scandinavica%22">Acta Physiologica Scandinavica</searchLink>. Aug2004, Vol. 181 Issue 4, p383-390. 8p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Calcium%22">Calcium</searchLink><br /><searchLink fieldCode="DE" term="%22Cyclic+adenylic+acid%22">Cyclic adenylic acid</searchLink><br /><searchLink fieldCode="DE" term="%22Exocytosis%22">Exocytosis</searchLink><br /><searchLink fieldCode="DE" term="%22Renin%22">Renin</searchLink><br /><searchLink fieldCode="DE" term="%22Kidneys%22">Kidneys</searchLink><br /><searchLink fieldCode="DE" term="%22Physiology%22">Physiology</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: In this review we aim to give a comprehensive overview over the current knowledge of the cellular control of renin release. We hereby focus on the inhibitory effects of calcium on the exocytosis of renin. After a short introduction into general aspects of the regulation of renin release, including a brief summary on the role of the second messengers cAMP and cGMP, we will discuss parts of the literature on the effects of calcium on the renin system together with recent studies from our laboratory, investigating putative calcium influx and extrusion pathways of juxtaglomerular cells. Finally, as the precise mechanisms by which calcium inhibits the exocytosis of renin are far from being understood, we will present some hypotheses on the intracellular events being involved in the suppression of renin release by calcium. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Acta Physiologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=13952699 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1111/j.1365-201X.2004.01309.x Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 8 StartPage: 383 Subjects: – SubjectFull: Calcium Type: general – SubjectFull: Cyclic adenylic acid Type: general – SubjectFull: Exocytosis Type: general – SubjectFull: Renin Type: general – SubjectFull: Kidneys Type: general – SubjectFull: Physiology Type: general Titles: – TitleFull: Cellular mechanism of renin release. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Schweda, F. – PersonEntity: Name: NameFull: Kurtz, A. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 08 Text: Aug2004 Type: published Y: 2004 Identifiers: – Type: issn-print Value: 00016772 Numbering: – Type: volume Value: 181 – Type: issue Value: 4 Titles: – TitleFull: Acta Physiologica Scandinavica Type: main |
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