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Childhood adversity and borderline personality disorder: a meta‐analysis.

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Title: Childhood adversity and borderline personality disorder: a meta‐analysis.
Authors: Porter, C. (AUTHOR), Palmier‐Claus, J. (AUTHOR), Branitsky, A. (AUTHOR), Mansell, W. (AUTHOR), Warwick, H. (AUTHOR), Varese, F. (AUTHOR)
Source: Acta Psychiatrica Scandinavica. Jan2020, Vol. 141 Issue 1, p6-20. 15p. 1 Diagram, 4 Charts.
Subjects: Borderline personality disorder, Psychological abuse, Meta-analysis, Search engines
Abstract: Objective: The aim of this meta‐analysis was to better understand the magnitude and consistency of the association between childhood adversity and borderline personality disorder (BPD) across case–control, epidemiological and prospective cohort studies. Method: Following the review protocol (reference: CRD42017075179), search terms pertaining to adversity and BPD were entered into three search engines. Random‐effects meta‐analysis synthesised the size and consistency of the effects. Results: A total of 97 studies compared BPD to non‐clinical (k = 40) and clinical (k = 70) controls. Meta‐analysis of case–control studies indicated that individuals with BPD are 13.91 (95% CI 11.11–17.43) times more likely to report childhood adversity than non‐clinical controls. This effect was smaller when considering retrospective cohort (OR: 2.59; 95% CI 0.93–7.30) and epidemiological (OR: 2.56, 95% CI 1.24–5.30) studies. Findings were significant across adversity subtypes with emotional abuse (OR: 38.11, 95% CI: 25.99–55.88) and neglect (OR: 17.73, 95% CI = 13.01–24.17) demonstrating the largest effects. Individuals with BPD were 3.15 (95% CI 2.62–3.79) times more likely to report childhood adversity than other psychiatric groups. Conclusions: This meta‐analysis corroborates theoretical proposals that exposure to adverse life experiences is associated with BPD. It highlights the importance of considering childhood adversity when treating people diagnosed with BPD. [ABSTRACT FROM AUTHOR]
Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Childhood adversity and borderline personality disorder: a meta‐analysis.
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  Data: <searchLink fieldCode="AR" term="%22Porter%2C+C%2E%22">Porter, C.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Palmier‐Claus%2C+J%2E%22">Palmier‐Claus, J.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Branitsky%2C+A%2E%22">Branitsky, A.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Mansell%2C+W%2E%22">Mansell, W.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Warwick%2C+H%2E%22">Warwick, H.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Varese%2C+F%2E%22">Varese, F.</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Acta+Psychiatrica+Scandinavica%22">Acta Psychiatrica Scandinavica</searchLink>. Jan2020, Vol. 141 Issue 1, p6-20. 15p. 1 Diagram, 4 Charts.
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  Data: <searchLink fieldCode="DE" term="%22Borderline+personality+disorder%22">Borderline personality disorder</searchLink><br /><searchLink fieldCode="DE" term="%22Psychological+abuse%22">Psychological abuse</searchLink><br /><searchLink fieldCode="DE" term="%22Meta-analysis%22">Meta-analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Search+engines%22">Search engines</searchLink>
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  Label: Abstract
  Group: Ab
  Data: Objective: The aim of this meta‐analysis was to better understand the magnitude and consistency of the association between childhood adversity and borderline personality disorder (BPD) across case–control, epidemiological and prospective cohort studies. Method: Following the review protocol (reference: CRD42017075179), search terms pertaining to adversity and BPD were entered into three search engines. Random‐effects meta‐analysis synthesised the size and consistency of the effects. Results: A total of 97 studies compared BPD to non‐clinical (k = 40) and clinical (k = 70) controls. Meta‐analysis of case–control studies indicated that individuals with BPD are 13.91 (95% CI 11.11–17.43) times more likely to report childhood adversity than non‐clinical controls. This effect was smaller when considering retrospective cohort (OR: 2.59; 95% CI 0.93–7.30) and epidemiological (OR: 2.56, 95% CI 1.24–5.30) studies. Findings were significant across adversity subtypes with emotional abuse (OR: 38.11, 95% CI: 25.99–55.88) and neglect (OR: 17.73, 95% CI = 13.01–24.17) demonstrating the largest effects. Individuals with BPD were 3.15 (95% CI 2.62–3.79) times more likely to report childhood adversity than other psychiatric groups. Conclusions: This meta‐analysis corroborates theoretical proposals that exposure to adverse life experiences is associated with BPD. It highlights the importance of considering childhood adversity when treating people diagnosed with BPD. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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