Stria terminalis microstructure in humans predicts variability in orienting towards threat.
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| Title: | Stria terminalis microstructure in humans predicts variability in orienting towards threat. |
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| Authors: | Koller, Kristin (AUTHOR), Hatton, Christopher M. (AUTHOR), Rogers, Robert D. (AUTHOR), Rafal, Robert D. (AUTHOR) |
| Source: | European Journal of Neuroscience. Dec2019, Vol. 50 Issue 11, p3804-3813. 10p. 2 Color Photographs, 1 Black and White Photograph, 2 Charts, 1 Graph. |
| Subjects: | Diffusion tensor imaging, Microstructure |
| Abstract: | Current concepts of the extended amygdala posit that basolateral to central amygdala projections mediate fear‐conditioned autonomic alerting, whereas projections to the bed nucleus of the stria terminalis mediate sustained anxiety. Using diffusion tensor imaging tractography in humans, we show that microstructure of the stria terminalis correlates with an orienting bias towards threat in a saccade decision task, providing the first evidence that this circuit supports decisions guiding evaluation of threatening stimuli. [ABSTRACT FROM AUTHOR] |
| Copyright of European Journal of Neuroscience is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | Current concepts of the extended amygdala posit that basolateral to central amygdala projections mediate fear‐conditioned autonomic alerting, whereas projections to the bed nucleus of the stria terminalis mediate sustained anxiety. Using diffusion tensor imaging tractography in humans, we show that microstructure of the stria terminalis correlates with an orienting bias towards threat in a saccade decision task, providing the first evidence that this circuit supports decisions guiding evaluation of threatening stimuli. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 0953816X |
| DOI: | 10.1111/ejn.14504 |
